Pre clinical and clinical study to assess the role of Putrajeevakadi yoga with and without ksheerbasti on dhatukshayajanya bandhya w.s.r to diminishing ovarian reserve and defective endometrial receptivity
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 1) Changes in endometrial receptivity on the basis of Appelbaum uterine scoring system
研究概览
简要总结
RESEARCH QUESTION:
Is there any difference in the effect of Putrajeeevakadi yoga with and without Ksheerbasti in the management of Dhatukshayajanya bandhya W.S.R. to Dimnishing ovarian reserve and defective endometrial receptivity.
(Pre Clinical Study) Is there any difference in the effect Putrajeevakadi Yoga of with and without Ksheerabasti in the management of Dimnishing ovarian reserve and defective endometrial receptivity
NULL HYPOTHESIS(H0) : There is no differnce in the effect of Putrajeevakadi Yoga with and without kheerbasti in the management of Dhatukshayjanya bandhya W.S.R. to Dimnishing ovarian resreve and defective endometrial receptivity.
(Pre Clinical Study) NULL HYPOTHESIS(H0): There is no difference in the effect in the effect of Putrajeevakadi yoga with and without ksheerbsti in the management of Dimnishnig ovarian reserve and defective endometrial receptivit
ALTERNATIVE HYPOTHESIS (HA): There is difference in the effect of Putrajeevakadi yoga with and without ksheerabasthi in the management of Dhatukshayajanya bandhya w.s.r to Diminishing ovarian reserve and defective endometrial receptivity.
(Pre Clinical Study) ALTERNATIVE HYPOTHESIS (HA): There is difference in the effect of Putrajeevakadi yoga with and without ksheerabasthi in the management of Diminishing ovarian reserve and defective endometrial receptivity.
AIM: To evaluate the Effect of Putrajeevakadi yoga with and without Ksheerbasti in the management of Dhathukshayajanya Bandhya w.s.r to Diminishing Ovarian Reserve and def ctive Endometrial Receptivity. (Pre Clinical Study) AIM: To evaluate the Effect of Putrajeevakadi yoga with and without Ksheerbasti in the management of Diminishing Ovarian Reserve and defctive Endometrial Receptivity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Patients having primary or secondary infertility will be selected.
- •2.Patient diagnosed as diminishing ovarian reserve as per Poseidon criteria or Defective endometrial receptivity as per Applebaum score.
排除标准
- •Patients having age less than 21 years and more than 40 years.
- •Known case of Fragile x syndrome.
- •Patient suffering from disorders of reproductive tract like active Tuberculosis, Carcinoma.
- •Patient with anatomical defect.
- •Patient suffering from any chronic systematic illness like chronic anaemia, HTN (BP more than 140/90 mm Hg ).
- •Sexually transmitted diseases such as HIV, VDRL, HBsAg etc.
- •Patients Ayogya (contraindicated) for Yoga Basti.
结局指标
主要结局
1) Changes in endometrial receptivity on the basis of Appelbaum uterine scoring system
时间窗: two weeks
by USG Doppler
时间窗: two weeks
2) No. of follicle/ Basal AFC, Size of Dominant follicle by trans vaginal sonography
时间窗: two weeks
3) Changes in Basal serum AMH level.
时间窗: two weeks
4) Changes in LH/FSH value and ratio.
时间窗: two weeks
5) Changes in the Basal Serum Estradiol.
时间窗: two weeks
次要结局
- 1. conception rate(2. Improvement in menstrual disorder/problem, if present previously.)
研究者
Rashmi nema
National institute of ayurveda jaipur