Carbohydrate intake and refeeding syndrome in children and adolescents with anorexia nervosa

Not Applicable

• Conditions: Eating disorder - anorexia nervosa; Mental Health - Eating disorders

• Registration Number: ACTRN12621000300875
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-10-22
• Study Start: 2021-03-18
• Last Update Posted: 22 March 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

diagnosis of anorexia nervosa (restrictive or atypical) as per DSM-V
- patients admitted to the Paediatric and Adolescent medical ward
- 18 years of age or less
- expected to be inpatient for a minimum of 7 days
- managed according to the standard eating disorders protocol on medical ward

Exclusion Criteria

- >19 years of age
- patients not meeting criteria for diagnosis of anorexia nervosa as per DSM-V
- patients transferred from another hospital where nutrition rehabilitation has already started
- patients with low phosphate on admission
- patients not managed according to the usual eating disorder protocol
- patient or parent not willing to consent to the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of hypophosphatemia.<br>Blood sample taken as per standard practice by pathology nurse.<br>Serum phosphate result recorded on Cerner and transferred to data collection sheet by dietitian. <br>[Daily during first 7 days of admission.]

Secondary Outcome Measures

Name	Time	Method
Comparison of weight changes in week one and over course of admission.<br>Weight measured using digital scale. Participants weighed backwards by nursing staff so as not to see weight. [Weight taken at baseline and twice weekly thereafter until discharge (this is usual care). ];Composite secondary outcome - changes to other biochemical markers associated with refeeding syndrome (i.e potassium and magnesium).[Bloods measured at baseline, then daily for first 7 days of admission, and then twice weekly thereafter until discharge (this is usual care).<br> ];Changes to blood glucose levels associated with refeeding syndrome. [Blood glucose level (BGL) measured four times a day for first week of admission. ]