Evaluation of Serum Chemokines for Patients Undergoing Treatment With Boceprevir.
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Level (ng/mL) of serum chemokines.
研究概览
简要总结
The purpose of the study is to determine differences in levels of serum chemokines from patients undergoing treatment with Boceprevir. The aim is to determine if non-responders have significantly different levels of chemokines than responders.
详细描述
Patients undergoing standard of care at the UNC Liver Center are consented for collection of an additional serum sample under the UNC Liver Center serum and tissue bank study. These samples will be used to analyze differences in serum chemokines across responders and non-responders.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult patients (age 18 or older) treated with an antiviral Hepatitis C treatment regimen that includes Boceprevir.
排除标准
- •Inability to provide informed consent for a serum sample enrolled in the University of North Carolina Liver Center serum bank.
- •No pre and post serum sample available within 6 months of the treatment period.
结局指标
主要结局
Level (ng/mL) of serum chemokines.
时间窗: Baseline: <=6 months prior to start of treatment and Post-treatment: <=6-months after the last dose
Compare levels of serum chemokines across Boceprevir responders (SVR) and non-responders for both Baseline (\<=6-months pre-treatment) and Post-treatment (\<=6-months post-treatment).
次要结局
未报告次要终点