Evaluation of serum levels of chemokines during interferon beta treatment in multiple sclerosis patients
Completed
- Conditions
- Multiple sclerosisNervous System Diseases
- Registration Number
- ISRCTN45526724
- Lead Sponsor
- Foundation to Support Education, Research and Assistance (Fundação de Apoio ao Ensino, Pesquisa e Assistência [FAEPA]) (Brazil)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Patients with multiple sclerosis diagnosed by McDonald criteria 2001
2. Aged between 18 and 50 years old
3. Up to ten years of disease
4. Up to 5 points on the Expanded Disability Status Scale (EDSS)
5. At least one gadolinium enhacement lesion on magnetic ressonance or one clinical relapse in the year prior to study
Exclusion Criteria
1. Pregnancy
2. Ttreatment with immunossupressor regimen
3. Stability of disease more than one year
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of serum chemokines levels with patients and disease characteristics
- Secondary Outcome Measures
Name Time Method Comparison of serum chemokines levels with lesions by magnetic resonance imaging (MRI)