CTRI/2013/12/004179
Recruiting
Phase 3
Randomized Controlled Trial of Low-Dose Intravenous Cyclophosphamide versus Oral Mycophenolate Mofetil in Treatment of Lupus Nephritis.
Dr Manish Rathi0 sites100 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- Systemic lupus erythematosus-Lupus nephritis
- Sponsor
- Dr Manish Rathi
- Enrollment
- 100
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients aged 12 to 65 year with diagnosis of Systemic Lupus Erythematosus by American College of Rheumatology criteria (ACR)
- •2\. Kidney biopsy diagnosis of Lupus nephritis class III, IV, V, III\+V, IV\+V
- •3\.Serum creatinine \<3\.0 mg/dl.
Exclusion Criteria
- •1\. Severe proliferative lupus nephritis on histology (eg. Crescentic glomerulonephritis)
- •2\. Ongoing infection
- •3\. Pregnant females
- •4\. Previously received immunosuppressive treatment
- •5\. Patient not giving consent
Outcomes
Primary Outcomes
Not specified
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