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临床试验/CTRI/2026/02/103002
CTRI/2026/02/103002尚未招募不适用

Effect Of Neuromuscular Electrical Stimulation Of Diaphragm On Maximal Inspiratory Pressure, Maximal Expiratory Pressure And Quality Of Life In Chronic Obstructive Pulmonary Disease Patients

JADI ROOPA1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年2月16日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Maximal Inspiratory Pressure, Maximal Expiratory Pressure

研究概览

简要总结

Chronic Obstructive Pulmonary Disease (COPD) is characterized by airflow limitation and respiratory muscle dysfunction, leading to reduced inspiratory and expiratory muscle strength and impaired quality of life. Weakness of the diaphragm plays a key role in exercise intolerance and dyspnea in patients with COPD. Neuromuscular electrical stimulation (NMES) has emerged as a potential adjunctive therapy to improve muscle strength and functional outcomes.

This study aims to evaluate the effect of neuromuscular electrical stimulation of the diaphragm on maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and quality of life in patients with COPD. This is a prospective, randomized, placebo-controlled, interventional clinical trial conducted on patients diagnosed with stable COPD. Eligible participants will be randomly allocated into two groups. The experimental group will receive diaphragm NMES along with conventional physiotherapy, while the control group will receive Sham stimulation along with conventional physiotherapy.

The intervention will be administered for three sessions per week for four weeks treatment period under supervised conditions. Outcome measures including MIP, MEP, and quality of life scores will be assessed at baseline and after completion of the intervention. The results of this study may provide evidence regarding the effectiveness of diaphragm NMES as an adjunct to conventional physiotherapy in improving respiratory muscle strength and quality of life in patients with COPD.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
50.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • •GOLD Classification of COPD Grade II and Grade III Breathlessness Patients who had not participated in rehabilitation In the past 6 months Normal intelligence and no communication barriers Willingness to participate.

排除标准

  • •History of recent exacerbation Dermic injury at electrode placement site Metallic prosthesis Coexisting neurological conditions Other respiratory conditions such as Pulmonary Tuberculosis Bronchial Asthma Pneumonia.

结局指标

主要结局

Maximal Inspiratory Pressure, Maximal Expiratory Pressure

时间窗: Baseline Pre intervention and Post intervention After four weeks

次要结局

  • Quality of life(Baseline Pre intervention and Post intervention After four weeks)

研究者

发起方
JADI ROOPA
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

JADI ROOPA

DURGABAI DESHMUKH HOSPITAL AND RESEARCH CENTRE

研究点 (1)

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