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Efficacy of rose Bengal dye in addition with mechanical cleaning using laser assisted therapy in implant defects.

Phase 2
Conditions
Health Condition 1: K055- Other periodontal diseases
Registration Number
CTRI/2024/04/065478
Lead Sponsor
Dr Nivedha
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1 patients above or equal to 20years of age.

2 Absence of relevant medical conditions.

3 Initial peri-implantitis a pocket probing depth (PPD) of 4–6 mm with concomitant bleeding on probing (BoP) at 1 peri-implant site and radiographic marginal bone loss ranging from 0.5 to 2 mm between delivery of the suprastructure and pre-screening appointment.

4 Implant in function for at least 1 year.

5 Solid screw bone level titanium implants with sandblasted and acid etched surface (Straumann dental implant system)

Exclusion Criteria

(1) Uncontrolled medical conditions.

(2) Pregnant or lactating females.

(3) Tobacco smoking.

(4) Untreated periodontal conditions.

(5) Use of antibiotics in the past 3 months.

(6) Subjects treated for more than 2 weeks with any

medication known to affect soft tissue conditions (e.g. phenytoin, calcium antag- onists, cyclosporin, coumadin and non- steroidal anti-inflammatory drugs) within 1 month of the baseline examination.

(7) Peri-implant mucositis defined as the absence of radiographic marginal bone loss between delivery of the suprastructure and pre-screening appointment.

(8) Failure to sign written informed consent.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1) Pocket Probing Depth (PPD). <br/ ><br>(2) Clinical Attachment Level (CAL). <br/ ><br>(3) Mucosal recession (REC). <br/ ><br>(4) Bleeding on Probing (BoP) <br/ ><br>(5) Modified Plaque Index (mPlI)Timepoint: Baseline <br/ ><br>3 months <br/ ><br>6 months
Secondary Outcome Measures
NameTimeMethod
Microbial colony count <br/ ><br>Inflammatory bio marker levelsTimepoint: Baseline <br/ ><br>3 months <br/ ><br>6 months
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