NL-OMON39347已完成不适用
The role of miRNAs in the biology of Barrett*s esophagus - The role of miRNAs in the biology of Barrett*s esophagus
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •For the group with advanced esophageal adenocarcinoma > stage 1A :
- •Patients older than 18 years with esophageal adenocarinoma with stage 1B or higher that are scheduled for esophagogastroduodenoscopy.
- •For the high-grade dysplasia or esophageal adenocarcinoma group:
- •Patients older than 18 years with Barrett's esophagus and esophageal adenocarinoma until stage 1A (established on the basis of a histological biopsy) that are scheduled for esophagogastroduodenoscopy.
- •For the non-dysplastic Barrett's esophagus group:
- •Patients older than 18 years with long-standing non-dysplastic Barrett's esophagus that are under surveillance and have not shown any signs of malignant progression.
- •For the gastro-esophgeal reflux disease group patients:
- •Patients older than 18 years without Barrett's esophagus but with reflux disease, confirmed by an esophagogastroduodenoscopy
- •For the control group patients:
- •Patients older than 18 years without Barrett's esophagus or reflux disease, confirmed by an esophagogastroduodenoscopy
排除标准
- •Patients younger than 18 years
- •Patients unfit to undergo esophagogastroduodenoscopy.
- •Patients in whom no samples of either squamous epithelium, Barrett's esophagus or esophageal adenocarcinoma epithelium could be obtained for different reasons, as judged by the endoscopist
- •For the gastro-esophgeal reflux disease group patients: the presence of Barrett's esophagus
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