Optical Biopsy of Human Skin in Conjunction With Laser Treatment

Completed

• Conditions: Squamous Cell Carcinoma; Seborrheic Keratosis; Basal Cell Carcinoma; Congenital Nevi; Malignant Melanoma; Merkel Cell Carcinoma; Atypical Nevi; Paget's Disease; Dermatofibroma; Tattoos
• Interventions: Device: Optical Biopsy imaging

• Registration Number: NCT00540566
• Lead Sponsor: University of California, Irvine

Brief Summary

This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.

Detailed Description

The Optical measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement requires less than 5 minutes to execute. The measurements will be taken before and after skin treatment.This non-invasive, non-contact technique has great potential as a means to diagnose different skin problems without the need to obtain a piece of tissue from the skin.

Study Timeline

• Study Start: 1999-06
• Study First Submitted: 2007-10-04
• Study First Submitted QC: 2007-10-04
• Study First Posted: 2007-10-08
• Primary Completion: 2008-06
• Study Completion: 2008-07
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-19
• Last Update Posted: 2022-10-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 113

Inclusion Criteria

• Male or female age > 18 years

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Exclusion Criteria

• current participation in any other investigational drug evaluation
• inability to understand and carry out instructions

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Optical Biopsy	Optical Biopsy imaging	Optical Biopsy imaging

Primary Outcome Measures

Name	Time	Method
normal skin	12 weeks

Trial Locations

Locations (1)

Beckman Laser Institute, Unversity of California Irvine; 🇺🇸 Irvine, California, United States