Optical Biopsy of Human Skin in Conjunction With Laser Treatment
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Malignant Melanoma
- Sponsor
- University of California, Irvine
- Enrollment
- 113
- Locations
- 1
- Primary Endpoint
- normal skin
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.
Detailed Description
The Optical measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement requires less than 5 minutes to execute. The measurements will be taken before and after skin treatment.This non-invasive, non-contact technique has great potential as a means to diagnose different skin problems without the need to obtain a piece of tissue from the skin.
Investigators
Beckman Laser Institute and Medical Center
J.S.Nelson, MD,PhD,Professor of Surgery and Biomedical Engineering
University of California, Irvine
Eligibility Criteria
Inclusion Criteria
- •Male or female age \> 18 years
Exclusion Criteria
- •current participation in any other investigational drug evaluation
- •inability to understand and carry out instructions
Outcomes
Primary Outcomes
normal skin
Time Frame: 12 weeks