Comparison of the Precision of Cardiac Output-measures at Random to Respiration, Synchronised With Expiration and Instructed Slow Exhalation, Obtained by Pulmonal Artery Catheter Thermodilution Technique With Cold Injection

Norwegian University of Science and Technology1 site in 1 country18 target enrollmentSeptember 2013

ConditionsHeart Diseases

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Heart Diseases
Sponsor: Norwegian University of Science and Technology
Enrollment: 18
Locations: 1
Primary Endpoint: The observed variance amongst the cardiac output measures
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The intention of this study is to determine whether the precision of the measure of cardiac output can be optimized by conducting the measurement while the participant is instructed to exhale slowly. This will be compared to measurements done at random to respiration and timed with the participant's spontaneous expiration.

Registry

clinicaltrials.gov

Start Date

September 2013

End Date

November 2013

Last Updated

9 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Norwegian University of Science and Technology

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Every patient that receives a pulmonary artery catheter (PAC) related to elective cardiac surgeries,
•informed and written consent to participation in the study in accordance with the Helsinki declaration
•hemodynamic stability

Exclusion Criteria

•Hemodynamical instability
•atrial fibrillation
•tricuspid insufficiency ≥ grade 2
•hemodialysis or other conditions where extra volume load can be negative,
•lack of ability to give a written consent to participate in the study

Outcomes

Primary Outcomes

The observed variance amongst the cardiac output measures

Time Frame: 1 hour

The measures will be obtained the first postoperative morning by pulmonary artery catheter thermodilution technique. In total 24 measurements will be done in each patient, i.e 8 measurements in each interventional series described later. The variance observed will create the foundation for calculating the precision of the measures.