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临床试验/NCT06104189
NCT06104189已完成不适用

Ultrafast MRI Radiomics to Classify Histological Factors and Subtypes of Breast Cancer

Korea University Ansan Hospital1 个研究点 分布在 1 个国家目标入组 225 人开始时间: 2021年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
225
试验地点
1
主要终点
The signal intensity of MRI according to histological factors and subtypes of breast cancer

研究概览

简要总结

The goal of this prospective study is to investigate the performance of ultrafast MRI radiomics in classifying histological factors and subtypes of breast cancer compared with standard MRI among radiologists with varying experience. The written informed consent was obtained from all participant. We extracted 1618 radiomic features from ultrafast and standard contrast-enhanced MRI before treatment. Classification of hormonal receptors, human epidermal growth factor receptor 2, and Ki67 status and subtypes was evaluated using the area under the receiver-operating characteristic curve (AUC) with the DeLong test.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
27 Years 至 86 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Diagnosed with invasive breast cancer

排除标准

  • Diagnosed with other cancer

结局指标

主要结局

The signal intensity of MRI according to histological factors and subtypes of breast cancer

时间窗: Baseline, pre-surgery

Quantitative image values obtained from ultrafast MRI show similar performance in classifying histological factors and subtypes compared with standard MRI.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bo Kyoung Seo

Professor

Korea University Ansan Hospital

研究点 (1)

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Prospective Ultrafast MRI Radiomics for Breast Cancer | 临床试验