Intensive Monitoring and Preemptive Intervention in the Maintenance of AVF

Not Applicable

• Conditions: Vascular Access Malfunction; Vascular Access Site Occlusion; Vascular Access Complication
• Interventions: Other: Intensified Monitoring

• Registration Number: NCT04418726
• Lead Sponsor: Shanghai Zhongshan Hospital

Brief Summary

Whether intensive monitoring and preemptive intervention has an positive clinical effect on arterio-venous fistula (AVF) maintenance is a new issue in hemodialysis (HD) patient management. This study aims to explore the clinical value of intensive monitoring and preemptive intervention on AVF, so to decide the best follow-up items and frequency.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-06
• Study Start: 2020-06-01
• Study First Submitted: 2020-06-01
• Study First Submitted QC: 2020-06-03
• Last Update Submitted: 2020-06-03
• Study First Posted: 2020-06-05
• Last Update Posted: 2020-06-05
• Primary Completion: 2021-05-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• patients on HD with AVF in Zhongshan Hospital, Fudan University

Exclusion Criteria

• with malignancies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intensive Monitoring and Preemptive Intervention	Intensified Monitoring	In this group patients receive intensive monitoring and preemptive intervention. AVF surveillance refers to using non-invasive devices to check for the haemodynamic consequences of stenosis by measuring Qa every month. Clinical assessment refers to monitoring for any presence of stenosis by (i) physical examination, by means of visual inspection and presence of abnormal thrill, bruit or pulse and (ii) checking for signs of access dysfunction during dialysis: difficult cannulation, increase in dynamic arterial or venous pressure, inability to achieve the prescribed dialysis blood pump flow (Qb), prolonged bleeding after needle removal, access recirculation or a drop in Kt/V. Preemptive intervention is performed as long as problems are recognized, including health education and timely surgery.

Primary Outcome Measures

Name	Time	Method
AVF patency rate	6 months	AVF patency rate

Secondary Outcome Measures

Name	Time	Method
AVF complication	12 months	AVF complication