MedPath

Self-Management of Chronic Depressive Symptoms in Pregnancy

Not Applicable
Completed
Conditions
Depression
Interventions
Behavioral: MOMS Program
Registration Number
NCT02953990
Lead Sponsor
Virginia Commonwealth University
Brief Summary

This study will provide information about the feasibility, acceptability, and preliminary effects of a biobehavioral self-management approach for perinatal depressive symptoms. This line of research will contribute to the body of knowledge about adjunctive therapies for depressive symptoms in pregnancy, a serious problem which contributes to poor maternal-child outcomes. Ultimately, this will contribute to the development and implementation of theoretically driven depression prevention/ resiliency building interventions and measurement of appropriate biobehavioral outcomes to determine the effectiveness of interventions.

Detailed Description

The investigators longitudinal mixed-methods study will use a one-group repeated measures intervention design coupled with qualitative methods to provide a comprehensive view of the feasibility, acceptability, and preliminary effects of the MOMS intervention. Semi-structured interviews, recruitment and retention numbers, and participant logs will be used to evaluate feasibility and acceptability of the intervention (Specific Aim 1). Recently collected archival comparison group data from an existing study will be used to contribute to explorations of preliminary effects of the intervention by comparing longitudinal psychobehavioral data, birth weight data (Specific Aims 2 and 3).

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
41
Inclusion Criteria
  • ≥ age 18;
  • self-report of depressive symptoms prior to pregnancy;
  • current depressive symptoms at a moderate-to-severe level, as defined by a score ≥10 on the Patient Health Questionnaire-9;
  • able to read, write, and understand English;
  • self-identify as black/African American (AA) or White;
  • absence of suicidal ideations (measured as low risk on the M.I.N.I. Neuropsychiatric Interview tool);
  • absence of pregnancy complications/physical conditions making physical activity (PA) inadvisable;
  • has not engaged in a consistent mindfulness-based PA routine during the pregnancy (such as yoga or similar activities more than once per month).
Read More
Exclusion Criteria
  • If individual does not meet the inclusion criteria listed above, they are ineligible for the study.
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
MOMS ProgramMOMS ProgramThe MOMS Program involves: (1) mindfulness of symptoms and goal-setting through a nurse-participant partnership, and (2) 12 weeks of weekly community-based group prenatal yoga classes (75 minutes each) and self-directed home activity. Participants will engage in 12 weeks of weekly community-based group prenatal yoga classes (75 minutes each) and self-directed home practice.
Primary Outcome Measures
NameTimeMethod
Recruitment Databaseline

# individuals who enrolled in study/ # individuals who expressed interest in the study

Edinburgh Postnatal Depression Scale (EPDS)baseline and end of 12 week intervention

Pregnancy-specific Depressive Symptoms/Perinatal-specific depressive symptoms were measured by the 10-item Edinburgh Postnatal Depression Scale (EPDS; Cox et al., 1987); scores range from0 to 30, and a score of≥10 is considered indicative of possible depressive symptoms.

AdherenceEnd of 12 week intervention

Measure of those who attended at least 50% of the yoga sessions (measured analyzing class rosters)

Retention Data18 weeks post-baseline

# of participants enrolled/ # of participants completing study

Completed InterviewsEnd of 6 week postpartum visit

The number of participants who completed the intervention and completed a postpartum semi-structured interview

Secondary Outcome Measures
NameTimeMethod
State-Trait Anxiety Inventory-State (STAI-S)baseline and at the end of the 12 week intervention

State Anxiety/ Anxiety was measured with the State Anxiety Form Y ; scores range from20 to 80, and higher scores indicate higher state anxiety.

Self-Efficacy for Physical ActivityBaseline visit to end of 12 week intervention visit

Self-Efficacy for Physical Activity: The Physical Activity Self-Efficacy Scale is an eight-question scale that contains items about self-management of physical activities and social support regarding physical activity. A higher score indicates higher self-efficacy. The scores may range form 0-90

StressChange from Baseline visit to end of 12 week intervention visit

Perceived Stress Scale (PSS): 10-item scale; scores range from 0 to 40, and higher scores represent higher perceived stress

Total # of Minutes in Physical Activity (Including Yoga)End of 12 week intervention

Adherence to physical activity aspect of intervention (including yoga)

Patient Health Questionnaire-9 (PHQ9)baseline and end of 12 week intervention

Depressive Symptoms/ Perceived stress was measured with the 10-item Perceived Stress Scale; scores range from 0 to 40, and higher scores represent higher perceived stress.

Maternal Fetal Attachment Scale (MFAS)baseline and at the end of the 12 week intervention

Maternal-Child Attachment/ Maternal-fetal/ child attachment was measured using the Maternal-Fetal Attachment Scale with wording adapted slightly for the postpartum use; scores range from 24 to 120,with higher scores indicating higher attachment.

Ruminations Response Scale (RRS-10)baseline and at the end of the 12 week intervention

Ruminations/ The Ruminative Responses Scale was used to measure ruminations; total scores range from 10 to 40, where higher scores indicate higher rumination.

Baby's Birth Weightpostpartum visit

Baby's birth weight in pounds per mother's report at postpartum visit

Trial Locations

Locations (1)

Virginia Commonwealth University School of Nursing

🇺🇸

Richmond, Virginia, United States

© Copyright 2025. All Rights Reserved by MedPath