The Effects of Nitrogen Protoxide + Sevoflurane and Oxygen + Sevoflurane Anesthesia on Corneal Endothelial in Pediatric Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- Change of corneal endothal number
研究概览
简要总结
To evaluate the mean changes in Endothelial Cell and Corneal pachymetry in eyes that operated under N2O + sevoflurane and O2 + sevoflurane general anesthesia.
详细描述
40 eyes of 40 patients who had extraocular surgery under general anesthesia will be included in this prospective study. Cell density, Cell variatio, Hexagonality rate and pachymetry specular microscopy results at before surgery and 1 week and 1 month after surgery will be analyzed. O2 (1 l/min) with 50% air and N2O (1 l/min) with 50% air will be applied to each group with flow rate 2 l/min totally, respectively. The duration of surgery will be recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 5 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •40 eyes of 40 pediatric patients who had extraocular surgery under general anesthesia
排除标准
- 未提供
结局指标
主要结局
Change of corneal endothal number
时间窗: after surgery at first day, 1th week and 1th month
Nitrogen protoxide and oxygen may be change this number
Change of Cell density rate
时间窗: after surgery at first day, 1th week and 1th month
Nitrogen protoxide and oxygen may be change this rate
Change of Cell variation rate
时间窗: at before surgery and 1 week and 1 month after surgery
Nitrogen protoxide and oxygen may be change this rate
Change of Hexagonality rate
时间窗: after surgery at first day, 1th week and 1th month
Nitrogen protoxide and oxygen may be change this rate
Change of pachymetry specular microscopy results
时间窗: after surgery at first day, 1th week and 1th month
Nitrogen protoxide and oxygen may be change these results
次要结局
未报告次要终点