A trial to assess risk of dengue and evaluate a mosquito control intervention in northeastern Thailand
- Conditions
- DengueInfections and Infestations
- Registration Number
- ISRCTN73606171
- Lead Sponsor
- orwegian University of Life Sciences
- Brief Summary
2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/29458406 protocol 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34043621/ (added 11/07/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 539
Village:
Within ring roads of each strata (city), populated residential areas.
Cluster:
All points of the cluster are at least 100 m from the nearest point of the village border.
Household:
1. Households that are permanently inhabited
2. Households that are built or re-populated during the study period
Individuals:
1. In households where household head has signed informed consent for household to participate in project
2. A travel history outside the village during the previous 7 days
3. Chronic diseases such as HIV/AIDS or cancer
4. Apparent inability to give informed consent, e.g., due to mental disability or other incapacity, or lack of a legally authorized representative
5. Disease with similar symptoms to dengue but with evident alternative explanation
6. Age >1 year old
Village:
1. Area <0.125 km2
2. Number of houses<100
3. Population <300
4. Coverage of residential area 70-80% (scattered housing)
5. Non-residential areas, e.g. agricultural fields, airport, industrial areas, commercial areas, (e.g. shopping malls), government offices, lakes. army camps, hospitals and schools.
Household:
1. Apartment buildings
2. Abandoned houses
3. Non-permanent households
Individual
1. Refusal to participate in the study
2. Age <1 year old
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Adult Index (AI), is measured by collecting the number of adult female Ae. aegypti and Ae. albopictus per house (combined species) collected both indoors and outdoors for 15 minutes each location (30 minute total collection time) using a battery-driven mechanical aspirator. Collections occur once every four months in all households and once every month in three repeat sentinel households per cluster.
- Secondary Outcome Measures
Name Time Method