Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Obstructive Sleep Apnea
- Sponsor
- VA Office of Research and Development
- Enrollment
- 225
- Locations
- 2
- Primary Endpoint
- Sleep Apnea Diagnosis Rate
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Sleep apnea is common among Veterans with cerebrovascular disease (stroke or transient ischemic attack [TIA]), leads to hypertension, and is associated with recurrent stroke and death. Although continuous positive airway pressure (CPAP) safely treats sleep apnea, few Veterans with cerebrovascular disease are diagnosed with sleep apnea or offered treatment.
Detailed Description
The project sought to evaluate whether a diagnostic and therapeutic intervention strategy among Veterans with cerebrovascular disease and hypertension using unattended polysomnography and auto-titrating CPAP with a targeted adherence evaluation and educational protocol resulted in: an improved rate of diagnosed sleep apnea, an improved rate of treated sleep apnea, and improved blood pressure control.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Stroke or Transient Ischemic Attack Hypertension
Exclusion Criteria
- •Prior diagnosis of sleep apnea or other sleep disorder
- •Life expectancy \< 6 months or Hospice
- •Non-English speaker
- •Unable/unwilling to use mask
- •Inability to give informed consent
- •Oxygen dependent COPD
- •Chronic renal failure with dialysis
- •Active Suicidal Ideation
Outcomes
Primary Outcomes
Sleep Apnea Diagnosis Rate
Time Frame: The entire study period (baseline and up to one-year)
The number of patients with a diagnosis of sleep apnea
Hypertension Control
Time Frame: One year
Medication-Adjusted Systolic Blood Pressure
Secondary Outcomes
- Sleep Apnea Treatment Rate(One year)