Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 225
- 试验地点
- 4
- 主要终点
- Sleep Apnea Diagnosis Rate
研究概览
简要总结
Sleep apnea is common among Veterans with cerebrovascular disease (stroke or transient ischemic attack [TIA]), leads to hypertension, and is associated with recurrent stroke and death. Although continuous positive airway pressure (CPAP) safely treats sleep apnea, few Veterans with cerebrovascular disease are diagnosed with sleep apnea or offered treatment.
详细描述
The project sought to evaluate whether a diagnostic and therapeutic intervention strategy among Veterans with cerebrovascular disease and hypertension using unattended polysomnography and auto-titrating CPAP with a targeted adherence evaluation and educational protocol resulted in: an improved rate of diagnosed sleep apnea, an improved rate of treated sleep apnea, and improved blood pressure control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stroke or Transient Ischemic Attack Hypertension
排除标准
- •Prior diagnosis of sleep apnea or other sleep disorder
- •Life expectancy < 6 months or Hospice
- •Non-English speaker
- •Unable/unwilling to use mask
- •Inability to give informed consent
- •Oxygen dependent COPD
- •Chronic renal failure with dialysis
- •Active Suicidal Ideation
结局指标
主要结局
Sleep Apnea Diagnosis Rate
时间窗: The entire study period (baseline and up to one-year)
The number of patients with a diagnosis of sleep apnea
Hypertension Control
时间窗: One year
Medication-Adjusted Systolic Blood Pressure
次要结局
- Sleep Apnea Treatment Rate(One year)