跳至主要内容
临床试验/NCT04204538
NCT04204538已完成不适用

Evaluation of Dietary Practices and Assessment of Nutritional Status and Associated Risk Factors for Metabolic Syndrome in the Young Adult Population of Rwanda

University Ghent1 个研究点 分布在 1 个国家目标入组 1,247 人开始时间: 2021年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,247
试验地点
1
主要终点
Prevalence of large waist circumference

研究概览

简要总结

Policy makers in Rwanda have recently highlighted the importance of promoting healthy diets and lifestyle in response to rapidly increasing rates of obesity. This project will provide evidence on shifts in diet and nutritional status in urban dwellers as compared to the traditional diet and lifestyle in rural areas as a basis for a targeted public health policy for Rwanda.

详细描述

Adequate diet has been known for many years to be a major lever to significantly decrease the risk for non-communicable diseases (NCD). However, mainly due to urbanization and improved economic status in low and middle income countries (LMICs), the traditional largely plant-based diets are being replaced by more energy-dense and nutrient poor diets, incorporating more animal foods and processed foods and fat, and with a decrease in consumption of fruits and vegetables and other plant based foods. This diet change together with a sedentary lifestyle are typical phenomena in LMICs that are driving the so-called nutrition transition that is typically accompanied by an increase in obesity and in NCD like metabolic syndrome, diabetes, cardiovascular diseases and cancer. In Rwanda, NCD lead to 36% of total deaths. Cancers, diabetes, cardiovascular diseases, and chronic respiratory diseases account for 82% of NCD deaths. The major risk factor is the raised blood pressure (34.4%) and the probability of dying between ages 30 and 70 years from those four main NCD is estimated to 19%.

The Government of Rwanda has installed an operational NCD unit in the Ministry of Health with a view to developing preventive strategies vis-à-vis the nutrition transition process in the country. It has been shown already that there is a need for adopting dietary behaviour change to prevent the epidemic of chronic diseases.

The aim of this PhD work is to contribute in generating evidence needed to develop targeted prevention strategies for NCD in a broader framework of informed health policy making in Rwanda.

Specific objectives:

  1. To identify the changes in eating habits of different socio- economic subgroups in adults living in Kigali, in comparison to their peers in rural areas;
  2. To assess nutritional status and body composition using several methods (BMI, skinfold thicknesses, sitting height and body build, fat and fat free mass), with the ultimate objective to establish population-body composition-derived BMI cut-offs for overweight and obesity in this population;
  3. To assess and compare the prevalence of common risk factors for non-communicable disease (high BMI, low fruit and vegetable consumption, low physical activity and high blood pressure) between rural and urban areas;
  4. To evaluate people's nutrition knowledge, aptitude and capacity (KAP), perception of obesity and normal weight and food insecurity levels as risks factors for adherence to healthy dietary practices and life style;
  5. To generate information to be used by governments to improve dietary habits and physical activity through targeted interventions.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Permanent residence of the selected urban or rural villages
  • Holding a valid health insurance card
  • Aged between 18 and 35 years
  • Signing informed consent form
  • Registration in city demographic system, since study participants will be selected from population registration cards at village level,
  • Accept enumerators for home visit and data collection
  • Accept to visit the laboratory for blood sample collection,
  • Not suffering from any chronic disease such as VIH/ AIDS, diabetes, asthma, etc.

排除标准

  • Lactating, pregnant, and recently delivering (less than six month-postpartum) women
  • Physical disabilities that can prevent participants from working
  • Mental disability such as clinically diagnosed depression, anxiety disorders, eating disorders and addictive behaviors.

结局指标

主要结局

Prevalence of large waist circumference

时间窗: Through study completion (an average of 6 months)

Large waist circumference \[\> 89 centimeters for women and \>102 centimeters for men\]

Prevalence of high triglyceride concentrations

时间窗: Through study completion (an average of 6 months)

High triglyceride level \[\>150 milligrams per deciliter (mg/dL)\]

Prevalence of high-density lipoprotein (HDL) cholesterol

时间窗: Through study completion (an average of 6 months)

Reduced high-density lipoprotein (HDL) cholesterol \[\< 40 mg/dL in men or \< 50 mg/dL in women\]

Prevalence of participants with nutrition knowledge

时间窗: Through study completion (an average of 6 months)

Nutritional knowledge of macronutrients, micronutrients, water intake, diet and disease will be collected using a multiple choice answers. Each question had one mark for every correct response chosen. Using a marking scheme for nutritional knowledge test the scores were rated on score percentages using eight cut off points, with scores less than 20% indicating a bad nutritional knowledge, 50-59% satisfactory and Excellent for those scoring 80% and more.

Prevalence of the different dietary patterns

时间窗: Through study completion (an average of 6 months)

Dietary patterns will be identified using exploratory factor analysis on the food groups collected using the semi-quantitative Food Frequency Questionnaire. The dietary pattern identified will differ from plant_based diet and legume_based diet to western diet.

Prevalence of high blood pressure

时间窗: Through study completion (an average of 6 months)

Increased blood pressure \[\> 130/85 mm Hg\]

Prevalence of high levels of fasting blood sugar

时间窗: Through study completion (an average of 6 months)

Elevated fasting blood sugar \[\>100 mg/dL\]

次要结局

  • Prevalence of Food Insecure Households(Through study completion (an average of 6 months))

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验