MedPath

The Effects of the Be Mindful Intervention in Previously Depressed Individuals Experiencing Subclinical Symptoms

Not Applicable
Completed
Conditions
Major Depressive Disorder, Recurrent, in Remission
Depressive Symptoms
Interventions
Behavioral: Be Mindful
Registration Number
NCT04740879
Lead Sponsor
State University of New York at Buffalo
Brief Summary

This study is designed to help individuals cope with their current depressive symptoms by providing them access to a 4-week online Mindfulness-Based Cognitive Therapy: Be Mindful. Research has shown that completion of the Be Mindful intervention can reduce depressive symptoms in a community sample, and this study aims to evaluate if it can also help reduce depressive symptoms in individuals with a confirmed history of depression. Participants will either receive the intervention at the start of the study or four months after the start of the study (i.e., at 3-month follow-up), which will allow research staff to assess if reductions in depression are due to the intervention or something else. Research staff will also evaluate if the reduction in depressive symptoms lasts over the three months following intervention, and will investigate possible reasons for the change in depression (i.e., why the intervention produces change).

Detailed Description

Participant outcome variables will be assessed weekly for the first month after baseline. This will include the primary dependent variable (i.e., depressive symptoms), but will also include variables that will be explored as potential mechanisms of change (i.e., mindfulness, decentering, rumination, worry, self-compassion, and dysfunctional attitudes). The final weekly assessment will represent the Post-Intervention assessment.

Brief follow-up assessments of the primary dependent variable will be given 1-month and 2-months after the final weekly questionnaire. There will be a 3-month assessment that measures potential mechanisms of change in addition to the primary dependent variable.

After the 3-month follow-up, the Waitlist Control condition will be given access to the intervention. All participants (i.e., in both conditions) will be asked to complete another month of weekly questionnaires. These questionnaires will be identical to the first set of weekly questionnaires, and will allow mechanisms of change to be evaluated in the Waitlist Control condition.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
137
Inclusion Criteria
  • currently experiencing mild to moderate depressive symptoms (Patient Health Questionnaire 9 Current scores between 5 and 14)
  • meet Diagnostic and Statistical Manual of Mental Disorders (fifth edition; DSM-5) criteria for Past Major Depressive Disorder (determined by clinical interview)
Exclusion Criteria
  • responses suggest they have never experienced a Major Depressive Episode
  • responses suggest they are not currently experiencing sub-threshold symptoms of depression
  • they state they are not open to learning mindfulness or meditation techniques
  • they indicate they are currently receiving therapeutic treatment for depression or stress management elsewhere
  • they indicate their age is not between 18 and 65
  • they state they do not currently live in New York State

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
InterventionBe MindfulThe Intervention condition will be provided with access to the 4-week online Mindfulness-Based Cognitive Therapy course "Be Mindful" immediately after randomization to group.
Waitlist ControlBe MindfulThe Waitlist Control condition will be provided with access to the 4-week online Mindfulness-Based Cognitive Therapy course "Be Mindful" approximately 4 months after randomization to group.
Primary Outcome Measures
NameTimeMethod
Mean Change in Depressive Symptoms from Baseline as Measured by the Patient Health Questionnaire 9 at 3-Month Follow-Upat regular intervals until 3-month follow-up (approximately 4-5 months after the start of the study)

Participants are asked to rate items on a scale of 0 (Not at all) to 3 (Nearly every day).

Mean Change in Depressive Symptoms from Baseline as Measured by the Patient Health Questionnaire 9 Post-Interventionweekly during intervention, approximately 1-2 months

Participants are asked to rate items on a scale of 0 (Not at all) to 3 (Nearly every day).

Secondary Outcome Measures
NameTimeMethod
Mean Change in Mindfulness from Baseline as Measured by the Five Factor Mindfulness Questionnaire Short Formthrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 1 (never or rarely true) to 5 (very often or always true).

Mean Change in Rumination from Baseline as Measured by the Ruminative Response Questionnairethrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 1 (Almost never) to 4 (Almost always).

Mean Change in Decentering from Baseline as Measured by the Toronto Mindfulness Scalethrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 0 (not at all) to 4 (very much).

Mean Change in Dysfunctional Attitudes from Baseline as Measured by the Dysfunctional Attitudes Scale (Short Form 1)through study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 1 (totally agree) to 4 (totally disagree).

Mean Change in Worry from Baseline as Measured by the Penn State Worry Questionnairethrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 1 (Not at all typical of me) to 5 (Very typical of me).

Mean Change in Dysfunctional Attitudes from Baseline as Measured by the Single-Item Self-Esteem Scalethrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 1 (Not Very True of Me) to 5 (Very True of Me).

Mean Change in Self-Compassion from Baseline as Measured by the Self-Compassion Scale Short Formthrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 1 (Almost never) to 4 (Almost always).

Mean Change in Dysfunctional Attitudes from Baseline as Measured by the Rosenberg Self-Esteem Scalethrough study completion, which can take up to 6 months

Participants are asked to rate items on a scale of 0 (strongly disagree) to 3 (strongly agree).

Trial Locations

Locations (1)

State University of New York at Buffalo (SUNY at Buffalo)

🇺🇸

Buffalo, New York, United States

© Copyright 2025. All Rights Reserved by MedPath