ACTRN12613001153707已完成未知
ong-term effects of a protein enriched diet with lean red meat combined with progressive resistance compared to resistance training alone on muscle and brain health and cognitive function in community-dwelling older adults.
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 152
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 65 Years 至 90 Years（—）
- 性别
- All
入选标准
- •Community-dwelling men and women aged 65 years and over. All participants enrolled in the study must also have received approval from their local physician to participate in the community-based intervention.
排除标准
- •Participants will be excluded on the following criteria: 1) aged <65 years; 2) current or prior participation in resistance exercise (>1 week) and/or moderate-intensity physical activity greater than or equal to 150 minutes per week in the past 3 months; 3) acute or terminal illness, including current (treated or untreated) cancer or surgery/cessation of chemotherapy/radiotherapy less than 12-months ago; 4) history of a recent low trauma fracture with functional impairment that would limit participation in the exercise program; 5) body mass index (BMI) >40; 6) use of insulin to treat diabetes; 7) chronic liver disease, coeliac or inflammatory bowel disease, including ulcerative colitis or Crohn’s disease; 8) recent use of corticosteroids (past 6 months); or 9) inability to commit to the study and its requirements. Participants will not be excluded if they were currently taking vitamin D supplements, but will be asked to take the vitamin D that was provided as part of the study.
- •Eligible participants will then be screened using the Short Portable Mental Status Questionnaire (SPMSQ) and the Geriatric Depression Scale (GDS) to evaluate whether they are cognitively healthy and have no signs of depression. Those with a score of greater than two on the SPMSQ and/or a score of greater than six on the GDS will be excluded from the study. Participants that remained eligible will then be required to obtain approval from their local doctor to clear them of any contraindicated medical conditions to exercise, based upon American College of Sports Medicine (ACSM) guidelines, to participate in the program. Finally, participants will be asked to provide a fasted, morning blood sample to confirm that their estimated Glomerular Filtration Rate (eGFR) was >45 mL/min/1.73m2.
研究者
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