Antidepressant effects of Celecoxib in the treatment of patients with colon cancer
Phase 3
- Conditions
- Major Depressive Disorder.Major Depressive episode
- Registration Number
- IRCT201508201556N79
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1-Confirmation of colon cancer;2-receiving chemotherapy 3- score lower than 20 in Hamilton Rating Scale for depression 4-Mild to moderate major depressive disorder based on DSM-5
Exclusin criteria: 1-psychosis or other psychiatric disorder 2-Receiving psychotropic medications,3- receiving any antidepressants during past one month or ECT during past two months 4-history of cardiovascular disease , 5-pregnancy or breast feeding, 6-thyroid diseases
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Baseline and weeks 2-4-6 after beginig of treatment. Method of measurement: by Hamiltion Depression Rating Scale 17-Item.
- Secondary Outcome Measures
Name Time Method Severity of pain. Timepoint: Baseline and weeks 2-4-6 after beginig of treatment. Method of measurement: by Visual Analogue Scale.