celecoxib in the treatment of depressed patients with brucellosis

Not Applicable

• Conditions: Major depressive disorder.; Major Depressive episode

• Registration Number: IRCT201405271556N59
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1-Confirmation of brucellusis, 2age between 18 to 50 years old, 3- score lower than 20 in Hamilton Rating Scale for depression 4-Mild to moderate major depressive disorder based on DSM-V
Exclusion criteria: 1-duration of brucellosis more than 3 months, 2-presence of localized brucellosis(including endocarditis, osteomyelitis), 3-psychotic disorder, 4-receiving psychotropic medications, 5-receiving antidepressants during the last month 6-receiving antibiotics during the last month, 7-patients who are under treatment with immunosuppressives, 8-history of cardiovascular disease, 9-pregnancy, 10-nursing women, 11-any significant medical condition(including malignancy, HIV infection, autoimmune disease,renal failure,hepatic failure), 12- other infectious diseases

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of depression. Timepoint: Baseline and weeks 2-4-8 after beginig of treatment. Method of measurement: by Hamiltion Depression Rating Scale 17-Item.