ROLE OF SPOT URINE SODIUM IN FUROSEMIDE STRESS TEST IN ICU PATIENTS WITH ACUTE KIDENY DISEASE AND FLUID OVERLOAD
Not Applicable
- Conditions
- Health Condition 1: N179- Acute kidney failure, unspecified
- Registration Number
- CTRI/2018/12/016723
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Acute kidney injury (AKI) - AKIN stage 1 and 2
2 Systolic BP > 100 mm Hg with or without vasopressors
3 Patients on norepinephrine infusion < 10 mcg per minute dose requirement
Exclusion Criteria
1 Pre existing CKD
2 AKI- AKIN stage 3
3 Significant Heart diseases including cardiac failure
4 Chronic liver disease
5 Significant hemodynamic instability
6 Hypotension SBP < 100 mm Hg with or without vasopressors
7 Patients on norepinephrine infusion > 10 mcg per minute dose requirement
8 Patients requiring 2 or more vasopressors
9 Major electrolyte disturbances
10 Na < 120, > 160 mmol/L
11 DI, SIADH and other major disorders affecting serum Na levels
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the correlation between change in urine spot sodium in response to Furosemide Stress Test (FST) and progression of acute kidney injury (AKI)Timepoint: 2,6 Hrs
- Secondary Outcome Measures
Name Time Method To assess the changes in urine spot sodium in response to Furosemide Stress Test (FST).Timepoint: 2, 6 Hrs;To assess the correlation between changes in urine spot sodium and urine output in response to Furosemide Stress Test (FST).Timepoint: 2, 6 Hrs;To assess the correlation between hourly urine output in response to Furosemide Stress Test (FST) and progression of acute kidney injury (AKI).Timepoint: 1,2 Hrs