Preoperative Neutrophil-lymphocyte Count Ratio in Prediction of the Grade of Lung Tumor.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Neutrophil-lymphocyte count ratio
研究概览
简要总结
The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading.
详细描述
Lung cancer remains as one of the leading causes of death among oncology patients. Close connection between inflammation and pathogenesis of some neoplasms was determined in a number of studies. Some studies show promise that ratio of neutrophil to lymphocyte count (NLCR) may be recognized as a prognostic marker for several carcinomas: renal, lung and colorectal. The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading. During routine preoperative blood tests complete blood count is done and NLCR, WBC, neutrophil and lymphocyte count is noted. After the thoracic surgery intervention and histopathological examination grading of lung tumor is noted.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •consecutive thoracic surgery patients with lung cancer grading confirmed by histopathology postoperatively
- •preoperative routine complete blood count analysis
排除标准
- •infectious disease
- •pregnancy
- •autoimmunologic disease
- •other known conditions or treatments that may influence the blood count (seropositivity for HIV, chemotherapy, and corticotherapy)
结局指标
主要结局
Neutrophil-lymphocyte count ratio
时间窗: From October 1, 2014 to October 15, 2018
Neutrophil-lymphocyte count ratio is measured during routine preoperative blood tests.
次要结局
- Neutrophil count(From October 1, 2014 to October 15, 2018)
- Lymphocyte count(From October 1, 2014 to October 15, 2018)
- Leucocyte count(From October 1, 2014 to October 15, 2018)
研究者
Piotr Palaczyński
Principal Investigator
Medical University of Silesia
