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临床试验/NCT03749512
NCT03749512已完成不适用

Preoperative Neutrophil-lymphocyte Count Ratio in Prediction of the Grade of Lung Tumor.

Medical University of Silesia1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2014年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
400
试验地点
1
主要终点
Neutrophil-lymphocyte count ratio

研究概览

简要总结

The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading.

详细描述

Lung cancer remains as one of the leading causes of death among oncology patients. Close connection between inflammation and pathogenesis of some neoplasms was determined in a number of studies. Some studies show promise that ratio of neutrophil to lymphocyte count (NLCR) may be recognized as a prognostic marker for several carcinomas: renal, lung and colorectal. The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading. During routine preoperative blood tests complete blood count is done and NLCR, WBC, neutrophil and lymphocyte count is noted. After the thoracic surgery intervention and histopathological examination grading of lung tumor is noted.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • consecutive thoracic surgery patients with lung cancer grading confirmed by histopathology postoperatively
  • preoperative routine complete blood count analysis

排除标准

  • infectious disease
  • pregnancy
  • autoimmunologic disease
  • other known conditions or treatments that may influence the blood count (seropositivity for HIV, chemotherapy, and corticotherapy)

结局指标

主要结局

Neutrophil-lymphocyte count ratio

时间窗: From October 1, 2014 to October 15, 2018

Neutrophil-lymphocyte count ratio is measured during routine preoperative blood tests.

次要结局

  • Neutrophil count(From October 1, 2014 to October 15, 2018)
  • Lymphocyte count(From October 1, 2014 to October 15, 2018)
  • Leucocyte count(From October 1, 2014 to October 15, 2018)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Piotr Palaczyński

Principal Investigator

Medical University of Silesia

研究点 (1)

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