Comparison between Direct Oral Anticoagulation (DOAC) Interruption and DOAC Continuation in Patients Undergoing Elective Invasive Coronary Angiography or Percutaneous Coronary Interventio

Recruiting

• Conditions: Chronic Coronary Syndrome; Coronary Artery Disease; 10011082

• Registration Number: NL-OMON51007
• Lead Sponsor: Zuyderland Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 1270

Inclusion Criteria

o Patients aged between 18-85 years using DOAC and undergoing elective ICA or
PCI.
o Written informed consent

Exclusion Criteria

- Patients initially presenting with Acute Coronary Syndrome (STEMI, NSTEMI, UA)
- Patients <18 or >85 years old
- Calculated CLCR <30 mL/min
- Patients simultaneously participating in another clinical trial
- History or condition associated with increased bleeding risk, as listed below:
o Major surgical procedure within 30 days before the procedure
o Known inaccessible radial artery during previous procedure
o History of GI bleeding in the previous 6 months
o History of intracranial, intraocular, spinal, or atraumatic intra-articular
bleeding
o Chronic bleeding disorder
o Known intracranial neoplasm, arteriovenous malformation, or aneurysm
o Known anemia with last measured haemoglobin value <6 mmol/L [9.67 g/dL]
o Current pregnancy or breast-feeding
o Known significant liver disease (e.g., acute clinical hepatitis, chronic
active hepatitis, cirrhosis), or ALT >3 x the ULN

Study & Design

• Study Type: Interventional
• Study Design: Not specified