Rosuvastatin for Intracranial Arterial Stenosis on Magnetic Resonace Angiography
Not Applicable
- Conditions
- Intracranial Arterial Stenosis
- Registration Number
- JPRN-UMIN000016202
- Lead Sponsor
- Department of Neurology. Tokyo Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
Any hemorrhagic stroke or hemorrhagic infarction Familial hypercholesterolemia Patients with uncontrolled angina pectoris or congestive heart failure Patients with severe liver or renal dysfunction Patients with a malignant tumor requiring treatment Patients with uncontrolled diabetes mellitus Patients with secondary dyslipidemia (due to corticosteroid etc) Patients with a history of myopathy Patients considered by the investigator to be unsuitable for participating in this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression of intracranial stenosis after two years
- Secondary Outcome Measures
Name Time Method Any stroke [ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage] Ischemic stroke or transient ischemic attack (TIA) Intracerebral hemorrhage or subarachnoid hemorrhage Death from any cause All vascular events (stroke, myocardial infarction, or other vascular events) The change in LDL-c level from baseline The change in HDL-c level from baseline Number of cerebral microbleeds on MRI Carotid intima-media thickness Ankle brachial index Brachial-ankle pulse wave velocity Adverse events and adverse drug reactions