NCT06599229进行中（未招募）不适用
Myocardial Perfusion Abnormalities in Hypertrophic Cardiomyopathy
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Peak hyperemic perfusion
研究概览
简要总结
The purpose of this study is to investigate whether myocardial microvascular perfusion in patients with hypertrophic cardiomyopathy improved after initiation of cardiac myosin inhibitor therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of hypertrophic cardiomyopathy
- •Subject being initiated on clinically-indicated cardiac myosin inhibitor therapy
排除标准
- •Pregnancy
- •Lactation
- •Allergy to ultrasound enhancing agent (lipid-stabilized) or regadenoson
- •Serious AE to regadenoson
- •Hypotension
- •Serious bradycardia not addressed by pacemaker
- •Moderate or greater reactive airways disease
研究组 & 干预措施
Patients with HCM initiated on cardiac myosin inhibitor therapy
Patients with HCM who are being initiated on cardiac myosin inhibitor therapy for clinically indicated reasons.
干预措施: myocardial contrast echo (Diagnostic Test)
结局指标
主要结局
Peak hyperemic perfusion
时间窗: 3 months
Myocardial contrast echo-derived myocardial blood flow at peak hyperemia (produced by regadenoson)
次要结局
- Resting myocardial perfusion(3 months)
研究者
Jonathan Lindner, MD
Professor of Medicine
University of Virginia
研究点 (1)
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