Evaluating Microvascular Dysfunction in Symptomatic Patients With HypertroPhic CaRdiomyopathy
Completed
- Conditions
- Hypertrophic Cardiomyopathy
- Registration Number
- NCT02994615
- Lead Sponsor
- Lawson Health Research Institute
- Brief Summary
Patients with hypertrophic cardiomyopathy are being compared to a control group. IMR will be assessed with a pressure wire. Clinical f/u at 3 months and 6 months and a 48 hour holter monitor.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 19
Inclusion Criteria
- Age 18-80
- Already have an indication for coronary angiography
- Previous diagnosis of hypertrophic cardiomyopathy (unless control)
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Exclusion Criteria
- Fractional flow reserve found to be significant (FFR < 0.8)
- Already have a condition associated with or likely to be associated with an elevated IMR (diabetes, cardiac syndrome X, takotsubo cardiomyopathy, hypertensive cardiomyopathy, severe aortic stenosis, STEMI)
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IMR in patients with hypertrophic cardiomyopathy (HCM) versus controls 1 day
- Secondary Outcome Measures
Name Time Method Number of ventricular tachycardia 6 months Measured during 48 h recording after 6 months
Shortness of breath - NYHA class Up to 6 months Chest pain - Canadian Cardiovascular Society (CCS) class Up to 6 months
Trial Locations
- Locations (1)
London Health Sciences Centre
🇨🇦London, Canada