Determination of activity and dimension of osteomyelitis/necrosis of the jaw by multi-parametric/dynamic PET/MRT
Not Applicable
- Conditions
- K10.2Inflammatory conditions of jaws
- Registration Number
- DRKS00013917
- Lead Sponsor
- niversitätsklinikum Tübingen, Radiologische Klinik, Diagnostische & Interventionelle Radiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting stopped after recruiting started
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
patients suspicious for osteomyelitis of the jaw, age: =18 years, situation before surgery, informed consent
Exclusion Criteria
Acute other illness such as infection, limited contractual capability, pregnancy, breast feeding women, contra-indication for MRT such as metallic implants, pacemaker etc, high sensitivity to noise or temperature, claustrophobia, contra-indication for MR-contrast agend gadolinium, adipositas (>150 kg body weight).
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of diagnostic value of the dynamic PET/MR in regard to determine correct extention and activity of osteomyelities/necrosis of the jaw. Correlation with histopathological data after surgery (gold standard).
- Secondary Outcome Measures
Name Time Method - Comparism of data from patients receiving bisphosphonate/denosumab therapy or showing osteoradionecrosis to identify pathophysiological differences. - Analysis of functional and metabolic parameters relating to time and cost reduction of diagnostic procedures. - Evaluation of PET/MR data relating to prognostic information for further clinical follow-up.