Effects of OzoneTherapy on Abdominal Fat Reductio

Phase 3

• Conditions: localized adiposity; E01.370.600.115.100.062.500

• Registration Number: RBR-9rx83cv
• Lead Sponsor: niversidade Potiguar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-09-08
• Study Start: 2022-04-05
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

In the inclusion criteria, participants must be aged between 25 and 45 years, Body Mass Index (BMI) between 18.5 and 29.99 (Normal to Overweight), not regular practitioners of physical activities and must have the ability to understand and preserved local sensitivity.

Exclusion Criteria

The exclusion criteria will apply to all participants who are allergic to ozone, are under dietary restriction (diet, dietary re-education, etc.), are using anti-inflammatory medications up to 1 week before the start of the study. If any of the volunteers need to take medication within 1 month after the start of the study, they will be discarded from the sample, present any contraindication related to ozone therapy, such as hyperthyroidism or decompensated arterial hypertension, severe anemia, recent bleeding of organs, cachexia and pathologies with high stress oxidative. Participants who do not agree with the procedures, present sensitivity disorder during therapy, or do not adapt to the schedules and procedures will be discontinued from the research.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
This study aims to evaluate the effects of ozone therapy in the treatment of fat located in the abdominal region of women, seeking to confirm what the literature mentions in relation to its therapeutic effects and to analyze in detail how the adipose tissue submitted to this therapy behaves, through of the results obtained in the ultrasonographic analyses, not yet described by scientific studies. A positive outcome is expected in the reduction of adiposity located in the abdominal region, with a decrease in perimetry, plicometry and ultrasonography values in the period after the application of therapy.

Secondary Outcome Measures

Name	Time	Method
Determine the ideal parameters, such as the amount of ozonized gas (in milliliters) to be injected, concentration of ozone in the gas mixture, number of injection points in the treated area, number of sessions and frequency, in order to obtain the best effects.