Transcranial Magnetic Stimulation in depression treatment

Recruiting

• Conditions: depression; major depressive disorder; 10027946

• Registration Number: NL-OMON35230
• Lead Sponsor: Sint Lucas Andreas Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

age from 18 yrs onward
unipolar depressive disorder
only the following medication is allowed: SSRI's, venlafaxine, mirtazapine, antihistamanics for sedation
medication to be kept constant during the trial

Exclusion Criteria

bipolar disorder, dysthymic disorder
suicidality
Use of beta-blockers, other antidepressants or psychotropic medication, thyroid hormone, benzodiazepines, anti-epileptics
history of epilepsy or epileptic abnormalities on EEG
intracranial metal, pacemaker
schizophrenia, addiction, mental handicap, not speaking Dutch
lefthandedness

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Percentage of change from baseline on the Hamilton Depression Rating Scale<br /><br>(HAMD, 17 items)<br /><br>2. Percentage of patients with clinical response (= 50 % reduction in HAMD<br /><br>score)<br /><br>3. Percentage of patients with partial clinical response (= 30 % reduction in<br /><br>HAMD score) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Emotion Recognition Task</p><br>