Visuo-Tactile Integration and Body Ownership in the Human Brain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Neuro-behavioral changes associated with vision-dependent alterations of body ownership, measured via brain activity (fMRI)
研究概览
简要总结
The present project exploits brain imaging and neuroscience robotics to investigate the role of quantifiable visual input on the relationship between visuo-tactile integration and body ownership (the feeling that "this" body belongs to "me").
详细描述
Observational study, fundamental research, multicentric, national. The analysis of questionnaires, self-reports, and brain imaging associated with the RHI is used to understand the influence of visual input on body ownership. To this aim, participants lay down in the magnetic resonance (MR) scanner (Figure 1B), are presented with visual stimuli (videos of the virtual rubber hand - visual stroking) simultaneously in real time with tactile stimuli (robotic stroking of the participant's hand - tactile stroking), and in combination or not with the measurement of autonomic arousal (GSR) associated with the observation of a video showing the virtual rubber hand in a threatening situation (e.g. a knife approaching the virtual hand - unconscious RHI effects). By means of structured questionnaires and semi-structured self-reports, participants (i) evaluate eventual sensations felt during the visuo-tactile stimulation and (ii) report the personal feelings and impressions about body ownership for the virtual rubber hand (conscious RHI effects).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •general health
- •personal interest
- •age between 18 and 55 years old
- •fulfil standard guidelines for fMRI studies
排除标准
- •history of seizures, epilepsy
- •specific medications or treatment
- •concomitant diseases (e.g. cardiopathy)
- •pregnancy
- •unexplained loss of consciousness
- •chronic headaches
- •neurological illnesses
- •head concussion,
- •presence of metal in the neck or head
- •implanted medical devices
- •drug abuse
- •inability to give consent
结局指标
主要结局
Neuro-behavioral changes associated with vision-dependent alterations of body ownership, measured via brain activity (fMRI)
时间窗: Through study completion, an average of 2 years
Analysis of objective measures of the RHI
次要结局
- Subjective Experience via VAS scale(Through study completion, an average of 2 years)
- Automatic response (skin conductance)(Through study completion, an average of 2 years)