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Clinical Trials/NCT05853523
NCT05853523
Completed
Phase 2

The Desensitizing Treatment Effects of the Laser and Ozone on Dentin Hypersensitivity: In-vivo Comparison

University of L'Aquila1 site in 1 country44 target enrollmentFebruary 27, 2021

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Dentin Sensitivity
Sponsor
University of L'Aquila
Enrollment
44
Locations
1
Primary Endpoint
Change from Baseline in Pain on the 10-point Visual Analogue Scale (VAS) immediately after treatment
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The goal of this split mouth clinical trial is to compare clinical efficacy of diode laser and gas ozone in the treatment of dentine hypersensitivity (DHS) of non-carious-cervical lesion. The main questions it aims to answer are:

  • gas ozone affects dentine hypersensitivity?
  • diode laser affects dentine hypersensitivity? Participants, affected of DHS , were treated with gas ozone and diode laser.The pain severity was quantified according to the Visual Analogue Scale (VAS) before and after the treatmens.
Registry
clinicaltrials.gov
Start Date
February 27, 2021
End Date
August 27, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Maurizio D'Amario

Dott. Maurizio D'Amario

University of L'Aquila

Eligibility Criteria

Inclusion Criteria

  • Stimulated dentine hypersensitivity greater than 6 on visual analogue scale (VAS)
  • DHS affected two teeth, not contiguous, of different mouth semiarch.

Exclusion Criteria

  • Periodontal surgery in the last 3 month
  • Use of desensitizing paste in the last 3 month
  • Pregnant or breastfeeding state
  • Teeth with caries, reconstructions, pulpits congenital anomalies, fracture, and occlusal interferences.

Outcomes

Primary Outcomes

Change from Baseline in Pain on the 10-point Visual Analogue Scale (VAS) immediately after treatment

Time Frame: 5 minutes

Two stimuli were adopted to assess the degree of dentine hypersensitivities: evaporative test and tactile test. For the evaporative test, the teeth were trigged by a single operator, experienced, and trained, with a jet of air at a pressure of 45-60 psi at a distance of 2 mm from the buccal surface for 35 s. For the tactile test, the pain was triggered using a probe gently touched the dentine exposed in mesiodistal direction. The patient quantified the pain with the visual analogue scale (VAS) giving a value in the range from 1 (minimum pain) to 10 (maximum pain). The highest value of the pain stimulated by the two methods was registered.

Pain on the 10-point Visual Analogue Scale (VAS) at 6 months from treatment

Time Frame: 6 months

Two stimuli were adopted to assess the degree of dentine hypersensitivities: evaporative test and tactile test. For the evaporative test, the teeth were trigged by a single operator, experienced, and trained, with a jet of air at a pressure of 45-60 psi at a distance of 2 mm from the buccal surface for 35 s. For the tactile test, the pain was triggered using a probe gently touched the dentine exposed in mesiodistal direction. The patient quantified the pain with the visual analogue scale (VAS) giving a value in the range from 1 (minimum pain) to 10 (maximum pain). The highest value of the pain stimulated by the two methods was registered.

Pain on the 10-point Visual Analogue Scale (VAS) at 3 months from treatment

Time Frame: 3 months

Two stimuli were adopted to assess the degree of dentine hypersensitivities: evaporative test and tactile test. For the evaporative test, the teeth were trigged by a single operator, experienced, and trained, with a jet of air at a pressure of 45-60 psi at a distance of 2 mm from the buccal surface for 35 s. For the tactile test, the pain was triggered using a probe gently touched the dentine exposed in mesiodistal direction. The patient quantified the pain with the visual analogue scale (VAS) giving a value in the range from 1 (minimum pain) to 10 (maximum pain). The highest value of the pain stimulated by the two methods was registered.

Study Sites (1)

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