To Reduce the Burden of Caregiving on Health Outcomes of Midlife Women: Asian American Family Caregivers of Persons Living With Alzheimer's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- Change in Lawton ADL/IADL Scale score from baseline
研究概览
简要总结
The purpose of the proposed study is to preliminarily evaluate Technology-based information and coaching/support program that is tailored for Asian American midlife women who are family caregivers of patients living with Alzheimer's disease (TACAD) in improving health outcomes of Asian American midlife women who are family caregivers of persons living with Alzheimer's disease (AACA) and their care recipients.
详细描述
The purpose of the proposed study is to preliminarily evaluate a technology-based program in improving health outcomes of Asian American midlife women who are family caregivers of persons living with Alzheimer's disease (AACA) and their care recipients.
The participants of this randomized clinical trial will be 60 self-reported AACA aged 40 to 65 years old who identify as Chinese or Korean; are family caregivers of People Living with Alzheimer Disease (PLAD); can read and write English, Mandarin Chinese or Korean; who reside in the U.S.; and have access to the Internet through computers or mobile devices. Participants will be recruited through both online and offline communities/groups for Asian Americans. The recruitment settings are identified through both Internet searches and recommendations by research team members. When potential participants of Phase 2 visit the project Web site (after receiving/reviewing a study announcement), they will be asked to review the informed consent. When participants click I agree to participate, they will have given their consent. No identity information, including IP addresses, will be attached to any of the individual or group data. Therefore, research participants will not be identifiable directly or through the identifying information linked to subjects. Only research staff will have access to the data. Phase 2 study consists of two groups of research participants: (a) a control group who does not use the technology-based program, but uses the information on Alzheimer's Disease and caregiving by the Alzheimer's Association website; (b) an intervention group who uses the technology-based program and the information by the Alzheimer's Association website. Both groups will participate in the study for 3 months. During the research process, both groups are asked to fill out the Internet survey questionnaire (through the REDCap system) at three times (pre-test, post-1 moth, and post 3-months); if requested, paper-and-pencil questionnaires will be provided/used, or research staff will assist in administering the Internet surveys over the phone. Data will be collected only through the Internet survey, and each survey takes about 20 to 30 minutes to complete. Only for the intervention group, weekly group and individual coaching/support (max 1hr/week) by culturally matched bilingual interventionists will be provided through the online forum and chatting functions on the project website, phone calls, or text messages through ethnic-specific communication apps, and the participants are asked to use the educational modules, virtual reality app, and online resources that are available on the project website. The data collected through the Internet surveys will be stored on the HIPAA compliant clouds maintained by The University of Texas at Austin. All documentation related to the study will be also stored on the HIPAA compliant clouds maintained by The University of Texas at Austin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •self reported Asian American midlife women who are family caregivers of persons living with Alzheimer's disease (AACA).
- •Participants will be included if, by self-report, they are Asian American women aged 40 to 65 years old who identify as Chinese or Korean;
- •are family caregivers of PLAD;
- •can read and write English, Mandarin Chinese or Korean;
- •who reside in the U.S.;
- •have access to the Internet through computers or mobile devices.
- •Participants must be providing at least 4 hours per day unpaid assistance, on average, for a community-dwelling person in the early-middle stage of illness (Clinical Dementia Rating of 1) for whom there is no plan for institutionalization in six months.
- •Caregivers may or may not reside with their care recipient.
排除标准
- •Those who used the AA website previously and/or participated in other studies related to AD will be excluded.
结局指标
主要结局
Change in Lawton ADL/IADL Scale score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This questionnaires measures instrumental activities of daily living. The Lawton IADL scale contains eight items, with a summary score from 0 (low function) to 8 (high function). Possible total score ranges from 0 (low function, dependent) to 8 (high function, independent) for women, and 0 through 5 for men. The higher the score, the greater the person's abilities.
Change in Social Readjustment Rating Scale (SRRS) score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This questionnaire asks about number the of events in the last 12 months. Total score range 0-41 and higher score correlates with higher stress.
Change in Multidimensional Caregiver Strain Index from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
Is a questionnaire that evaluates caregiver's health outcome. Total possible score range is 0-26. Higher score correlates with worse outcome.
Change in Acculturation Stress Scale (ASS) score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
Score range is 0-36. Higher score correlates with worse outcome (higher stress)
Change in Perceived Stress Scale score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
Measure of individual stress. Possible score range is 0-40 with higher scores indicating higher perceived stress.
Change in EQ-5D-5L scale score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This is a generic health status measure by the EuroQol Group to measure quality of daily life. It includes five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/ depression) with five responses for each dimension (no problem to extreme problems); each digit in the five-digit codes refers to the status of each dimension, ranging from 1 (no problem) to 5 (severe problem). Possible score ranges from 0 to 100. A higher score in the EQ-5D-5L indicated better health-related Quality of Life.
Change in Revised Memory and Behavior Problem Checklist score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This outcome measures behavioral and psychological symptoms of care recipients. Total possible score ranges between 0-96 with higher score correlating with worse outcome.
Change in Quality of Life Scale in Alzheimer's Disease score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This questionnaire assesses quality of life (QOL) in 13 domains on a one 4-point Likert scale. It is used as a self-report and surrogate-report instrument. It uses a scale of 1-4 (poor, fair, good, or excellent) to rate a variety of life domains, including the patient's physical health, mood, relationships, activities, and ability to complete tasks. Total possible score ranges 13 to 52.
Change in Midlife Women's Symptom Index from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This questionnaire measures physical and psychological symptoms during the last 6 months. It includes 73 questions that can be rated from 0-4. Possible score ranges from 0-292. Higher score correlates with worse outcome.
Change in Neuropsychological Inventory Questionnaire score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This questionnaire measures care recipients' mood status. This is a 12-item inventory assessing severity of mood states or behaviors reflecting mood. The severity scale has scores ranging from 1 to 3 points (1=mild; 2=moderate; and 3=severe) and the scale for assessing caregiver distress has scores ranging from 0 to 5 points (0=no distress; 1=minimal distress; 2=mild distress; 3=moderate distress; 4=severe distress; and 5=extreme distress). Total possible score ranges 0 to 144.
Change in Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) score from baseline
时间窗: Baseline, 1 months post intervention, 3 months post intervention
This questionnaire measures the cognitive status of care recipients. Total possible score ranges from 8-40. Higher score correlates with worse outcome.
次要结局
- Change in Pearlin Mastery, Loss, and Competence Scale score from baseline(Baseline, 1 months post intervention, 3 months post intervention)
- Change in Ways of Coping Scale score from baseline(Baseline, 1 months post intervention, 3 months post intervention)
- Change in Caregiver Assessment of Behavioral Skill Scale score from baseline(Baseline, 1 months post intervention, 3 months post intervention)
- Change in Caregiver Activity Survey score from baseline(Baseline, 1 months post intervention, 3 months post intervention)
研究者
Eun-Ok Im
Professor
University of Texas at Austin