Spatial Repellent and Malaria Attack Rates II

Not Applicable

• Conditions: Malaria; Infection - Studies of infection and infectious agents

• Registration Number: ACTRN12612001102864
• Lead Sponsor: Eijkman Institute for Molecular Biology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-10-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Children between 6 - 13 years of age
-Weight > 20 kg
-G6PD normal on a qualitative screen
-No severe anaemia
-No significant chronic illness
-Sleeps in village >90% of nights during any given month
-No plans for extended travel during study
-Willingness to sign informed consent

Exclusion Criteria

-Having severe / chronic disease
-G6PD deficiency

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcomes of this study are : <br>1.Malaria attacks rates among the volunteers in each intervention arm<br>The malaria attack in each subject will be checked weekly by performing blood smear. Subjects found malaria positive will be drop from the study[Time point: every week during the coil intervention];2.Malaria vector abundance, human blood indices, parity rates, sporozoites rate and Spatial repellent action<br>The above entomologic parameter will be monitored by Human landing Catch (HLC), larval collection, blood meal, and resting collection.[Time point: every other week during the coil intervention]

Secondary Outcome Measures

Name	Time	Method
1. Incident cases of acute slide-confirmed malaria among all residents reporting to the study clinic with complaint of illness analysed by coil assignment of the cluster in which they reside[Timepoint: throughout the 6-month duration of coil intervention];2.To measure indoor anopheline feeding activity according to coil assignment.<br><br>Twenty houses, 5 in each cluster, will be selected as sentinel sites for measuring vector abundance within study site. All mosquitoes landing on collectors (to include anophelines, and culicines) will be captured using mouth aspirators with the aide of a flashlight. These collections will be performed and specimens processed using standard methods: parity, CSP-ELISA.[Timepoint: once a week during the coil intervention]