Symptoms of Acute Coronary Syndrome in Medical Regulation

Completed

• Conditions: Acute Coronary Syndrome

• Registration Number: NCT05902130
• Lead Sponsor: Centre Hospitalier Régional Metz-Thionville

Brief Summary

The main objective was to analyze the impact of the gender of the attending physician in the differences in the management of ST+ ACS between men and women.

This study will be conducted in partnership with the interventional cardiology team of the CHR Metz-Thionville and SAMU (emergency call center) of Moselle, which has a detailed registry of coronary angiographies at the center. A retrospective observational study will be carried out over a "typical" period outside of covid at the CHR Metz Mercy (2021-2022) based on coronary angiographies performed in the context of ST+ ACS at the CHR of patients referred by the center 15.

The patient's medical record will be analyzed, going back to his call to the 15 via tape listening. The number of subjects required being calculated at 104 men and 104 women, these patients will be selected from the database of our cardiologist colleagues and we will match one man to one woman by comparing the delays of several items (1st medical contact, time of 1st ECG, medicalization or not, delay of call to the cardiologist, delay of coronary angiography...) according to the sex of the regulator. The consequences of a difference in management will be also evaluated by analyzing in-hospital mortality, mortality at 30 days of management, and functional sequelae at discharge (grades of dyspnea, disturbance of myocardial contractility, LVEF at discharge).

This study based on the differences in questioning according to the gender of the regulating physician would allow better identification of the factors that increase the delay in the management of ST+ ACS in women, and to find avenues of correction in order to limit the loss of opportunity for patients.

The patients included who are still alive will receive a notification of non-objection by mail.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-01
• Study First Submitted: 2023-05-22
• Study First Submitted QC: 2023-06-05
• Study First Posted: 2023-06-13
• Primary Completion: 2023-10-01
• Study Completion: 2023-10-01
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-22
• Last Update Posted: 2023-12-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 208

Inclusion Criteria

• patient with emergency coronary angiography for ST+ ACS
• having made a call to the Emergency Center for the same reason

Exclusion Criteria

• non-real ST+ ACS

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Delay between the call to the emergency center and the first contact with a physician	End of the call to the emergency center, less than 10 min	Delay (minutes:seconds)

Secondary Outcome Measures

Name	Time	Method
Dispatch of a medical ambulance (Y/N)	End of the call to the emergency center, an average of 20 min	Number (%)
Day 30 mortality	30 days after the call to emergency center	Number (%)
Delay between the call to the emergency center and the first electrocardiogram	At hospital discharge, an average of 2 hours	Delay (hours:minutes)
Delay between the call to the emergency center and the first coronary angiography	At hospital discharge, an average of 2 hours	Delay (minutes)
In-hospital mortality	30 days after the call to emergency center	Number (%)
Left Ventricular Ejection Fraction	At hospital discharge, less than 30 days	Percentage

Trial Locations

Locations (1)

CHR Metz-Thionville/Hopital de Mercy; 🇫🇷 Metz, France