A Randomized, Double Blind and Crossover Study Investigating the Effect of Whole Versus Processed Orange Consumption on Satiety in Healthy Volunteers
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Satiety Response
- Sponsor
- University of Reading
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- Self reported hunger and fullness score by Visual Analogue Scale
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.
Detailed Description
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.
Investigators
Jeremy Paul Edward Spencer
Professor of nutritional medicine
University of Reading
Eligibility Criteria
Inclusion Criteria
- •Gender: male or female(postmenopausal women only)
- •Age at start of the study: males ≥ 21and ≤ 65 years and females ≥ 50 and ≤ 65 years
- •Body Mass Index (BMI) ≥ 18.5 and ≤ 27 kg/m2
- •Apparently healthy: measured by questionnaire, no reported current or previous metabolic diseases or chronic gastrointestinal disorders
- •Reported dietary habits: no medically prescribed diet, no slimming diet, used to eating 3 meals a day
- •Reported intense sporting activities ≤ 10h/w
- •Reported alcohol consumption ≤21 units/w
- •Informed consent signed
- •Recruitment form filled out
Exclusion Criteria
- •Dislike, allergy or intolerance to test products
- •Possible eating disorder (measured by SCOFF questionnaire score \>1)
- •Eating habits questionnaire score \>14
- •Reported medical treatment that may affect eating habits/satiety
- •Pre menopausal women
Outcomes
Primary Outcomes
Self reported hunger and fullness score by Visual Analogue Scale
Time Frame: baseline to 2 hours
Secondary Outcomes
- Overall liking by '9 point hedonic scale'(baseline to 2 hours)