Evaluation Of Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Sponsor
- Assiut University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- The duration of mechanical ventilation
- Last Updated
- 8 years ago
Overview
Brief Summary
Chronic obstructive pulmonary disease is a common respiratory condition that is characterized by inflammation of the large and small peripheral airways , the alveoli and adjacent capillary networks. Severe airflow obstruction that imposes a significant load on the respiratory system is a major manifestation of Chronic obstructive pulmonary disease. The reduced expiratory airflow also causes air trapping at the end of expiration , producing alveolar pressure that are higher than atmospheric pressure before the next breath. This condition is intrinsic positive end-expiratory pressure .
Investigators
Nisreen Mtk
principal investigator
Assiut University
Eligibility Criteria
Inclusion Criteria
- •patient with acute exacerbation of Chronic obstructive pulmonary disease and respiratory failure who are intubated and mechanically ventilated.
Exclusion Criteria
- •patient with neuromuscular diseases.
- •patient with pulmonary vascular diseases e.g pulmonary embolism.
Outcomes
Primary Outcomes
The duration of mechanical ventilation
Time Frame: 1 month