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Clinical Trials/NCT03230617
NCT03230617
Unknown
Not Applicable

Evaluation Of Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients

Assiut University1 site in 1 country100 target enrollmentSeptember 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Disease, Chronic Obstructive
Sponsor
Assiut University
Enrollment
100
Locations
1
Primary Endpoint
The duration of mechanical ventilation
Last Updated
8 years ago

Overview

Brief Summary

Chronic obstructive pulmonary disease is a common respiratory condition that is characterized by inflammation of the large and small peripheral airways , the alveoli and adjacent capillary networks. Severe airflow obstruction that imposes a significant load on the respiratory system is a major manifestation of Chronic obstructive pulmonary disease. The reduced expiratory airflow also causes air trapping at the end of expiration , producing alveolar pressure that are higher than atmospheric pressure before the next breath. This condition is intrinsic positive end-expiratory pressure .

Registry
clinicaltrials.gov
Start Date
September 1, 2017
End Date
December 31, 2018
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nisreen Mtk

principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • patient with acute exacerbation of Chronic obstructive pulmonary disease and respiratory failure who are intubated and mechanically ventilated.

Exclusion Criteria

  • patient with neuromuscular diseases.
  • patient with pulmonary vascular diseases e.g pulmonary embolism.

Outcomes

Primary Outcomes

The duration of mechanical ventilation

Time Frame: 1 month

Study Sites (1)

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