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临床试验/NCT00772993
NCT00772993Unknown不适用

Efficacy of RNFL / Retinal Thickness Ratio by Cirrus OCT Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma

Yonsei University1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2008年10月最近更新:
适应症

试验速览

阶段
不适用
入组人数
400
试验地点
1
主要终点
Ratio of RNFL / Full thickness retina

研究概览

简要总结

Glaucoma is presumed to be an axonal disease which starts at the lamina cribrosa. This assumption has led to the monitoring of the retinal nerve fiber layer thickness for the diagnosis and monitoring of progression of glaucoma. However, varying disc size, myopia and tilted discs affect the thickness of the retinal nerve fiber layer. This study aims to ascertain the ration of the retinal nerve fiber layer against full retina as a predictor of glaucoma diagnosis and progression.

研究设计

研究类型
Observational
时间视角
Prospective

入排标准

年龄范围
10 Years 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Primary open angle glaucoma
  • Myopia with evidence of glaucoma
  • Normal controls

排除标准

  • Evidence of retinal disease
  • BCVA < 0.4
  • Secondary glaucoma due to intraocular inflammation
  • Lens induced glaucoma
  • Tumor induced glaucoma
  • Neovascular glaucoma

结局指标

主要结局

Ratio of RNFL / Full thickness retina

时间窗: 2 months

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (1)

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