Cornelian cherry fruit extract in patients with non-alcoholic fatty liver disease.

Phase 3

• Conditions: Condition 1: People with non-alcoholic fatty liver with grades 1, 2, 3. Condition 2: People with non-alcoholic fatty liver with grades 1, 2, 3.; Nonalcoholic steatohepatitis (NASH); Fatty (change of) liver, not elsewhere classified; K75.81; K76.0

• Registration Number: IRCT20220726055558N1
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

ALT levels more than U/L 30 in men a
age 25-65 years
diagnosis of NAFLD and patients with grade 1, 2 and 3 fatty liver
willingness and consent of the person to participate in the study
Being a native of Yazd
ALT levels greater than U/L 19 in women

Exclusion Criteria

History of diseases including liver cirrhosis, viral hepatitis, cardiovascular diseases
History of taking drugs, including corticosteroids, or any drug affecting blood sugar
any drug or supplement affecting the liver within 1 month before the study
history of following a specific diet within 1 month before the study
breastfeeding and pregnancy
alcohol consumption

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Interleukin 6. Timepoint: Before the intervention and the end of the intervention after 12 weeks. Method of measurement: Measurement of plasma glutathione peroxidase by ELISA method.;Glutathione peroxidase. Timepoint: Before the intervention and the end of the intervention after 12 weeks. Method of measurement: Measurement of plasma glutathione peroxidase by ELISA method.

Secondary Outcome Measures

Name	Time	Method
Waist circumference. Timepoint: Before the intervention and the end of the intervention after 12 weeks. Method of measurement: Inflexible meter.;Hip circumference. Timepoint: Before the intervention and the end of the intervention after 12 weeks. Method of measurement: Inflexible meter.;Weight. Timepoint: Before the intervention and the end of the intervention after 12 weeks. Method of measurement: SECA scales.