Effects of Annurca apple polyphenols on cholesterol excretio

Completed

• Conditions: Metabolic Syndrome (MeTS); Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN13396702
• Lead Sponsor: Samnium Medical Cooperative

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-11-09
• Last Update Posted: 27 November 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Men and women between 18-83 years of age, of white race, with the following range values of serum cholesterol parameters at baseline (week 0):
1. TC, 200-260 mg/dL
2. HDL-C, 30-45 mg/dL
3. LDL-C, 189-206 mg/dL
4. TG, 170-280 mg/dL
5. Body mass index (BMI) between 18 and 30 kg/m2

Exclusion Criteria

Healthy adults (males and females) with:
1. Smoking
2. Obesity (BMI >30 kg/m2)
3. Diabetes
4. Hepatic disease
5. Renal disease
6. Heart disease
7. Family history of chronic diseases
8. Drug therapy or supplement intake for hypercholesterolemia
9. Drug therapy or supplement intake containing apple polyphenols
10. Heavy physical exercise (>10 h/week)
11. Pregnant women, women suspected of being pregnant, women who hoped to become pregnant, breastfeeding
12. Birch pollen allergy
13. Use of vitamin/mineral supplements 2 weeks prior to entry into the study
14. Donation of blood less than 3 months before the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified