Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse

Not Applicable

Completed

• Conditions: The Retention of Iodine in Saliva Over the Time; The Comparison of Iodine in Saliva Between Gargle and Swab

• Registration Number: NCT06272019
• Lead Sponsor: Chulalongkorn University

Brief Summary

To compare the iodine remaining in saliva between gargle method and swab method

Detailed Description

separate the participant in 2 groups group 1 use iodine gargle with gargle method, after 48 hours use iodine gargle with swab method group 2 use iodine gargle with swab method, after 48 hours use iodine gargle with gargle method The researcher will collect saliva before use iodine gargle and after use at time 0, 5, 10, 20, 30, 60, 120 minutes

Study Timeline

• Study Start: 2023-09-01
• Study First Submitted: 2024-02-14
• Study First Submitted QC: 2024-02-21
• Study First Posted: 2024-02-22
• Status Verified: 2024-04
• Primary Completion: 2024-04-20
• Study Completion: 2024-04-20
• Last Update Submitted: 2024-04-20
• Last Update Posted: 2024-04-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Thai people
• no underlying disease, no pregnant
• at least 24 teeth
• No use iodine gargle
• No allergy to iodine and seafood
• No orthodontic and prosthetic treatment
• No ulcer and edentulous area
• Saliva flow rate in male (0.57+-0.3 ml/minute), in woman (0.41+-0.27 ml/minute)
• PI score lower than 0.6 (Green and vermillion index)

Exclusion Criteria

• treatment orthodontic or prosthetic treatment currently
• Allergy to iodine between reach
• Can not participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
The rate of retention of iodine in saliva	0, 5, 10, 20, 30, 60 and 120 minutes	The retention of iodine in saliva after get the gargle (show in percentage)
The comparison of the retention of iodine between gargle and swab	0, 5, 10, 20, 30, 60 and 120 minutes	The comparison of rate of retention of iodine in saliva between gargle and swab (show in percentage)

Trial Locations

Locations (1)

Faculty of Dentistry, Chulalongkorn University; 🇹🇭 Bangkok, Thailand