To study the effect of transcranial direct current stimulation on urges to smoke tobacco among opioid dependent smokers.

Phase 2

• Conditions: Health Condition 1: F172- Nicotine dependenceHealth Condition 2: F112- Opioid dependence

• Registration Number: CTRI/2018/11/016339
• Lead Sponsor: I

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Right handed

Patients maintained on Buprenorphine for more than or equal to 3 months

Current daily users of Tobacco by smoking route (Defined as Daily use of beedis or cigarettes

in the past 1 month)

Nicotine dependence as per ICD 10 criteria

Minimum duration of Tobacco smoking is more than or equal to 1 year

Smoking more than or equal to 10 cigarettes or beedis or both per day

Willing to give informed consent

Exclusion Criteria

Current smokeless tobacco users (defined as using smokeless tobacco in past 1 month)

Currently undergoing tobacco cessation treatment (in past 1 month)

Current use of Benzodiazepines, Heroin, Tramadol, Dextropropoxyphene as confirmed by Urine Casette test

Current alcohol harmful use or dependence (as per ICD 10 criteria based on History)

Current cannabis harmful use or dependence (as per ICD 10 criteria based on History)

History of significant head injury, epilepsy, major psychiatric or neurological illness

(Based on history)

Presence of any metallic implants or devices or metalic rods or pacemakers, etc. (Based on

history and physical examination)

Inability to give consent (Due to Mental retardation / any illness )

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1) Baseline tobacco craving by Brief Questionnaire of Smoking Urges (BQSU) <br/ ><br>2) Cue induced tobacco craving by Visual Analog ScaleTimepoint: Before 1st session of tDCS <br/ ><br>After 1st session of tDCS <br/ ><br>After 5th session of tDCS

Secondary Outcome Measures

Name	Time	Method
umber of beedi/cigarette consumed per dayTimepoint: Before 1st session of tDCS and After 5th session of tDCS