Effect of Standardized Nutrient Management on Clinical Outcomes of Hematopoientic Stem Cell Transportation Patients

• Conditions: Nutrition Related Cancer
• Interventions: Dietary Supplement: dietary advice, oral nutritional supplement, supplementary parenteral nutrition or total parenteral nutrition

• Registration Number: NCT04591340
• Lead Sponsor: The Third Xiangya Hospital of Central South University

Brief Summary

To analysis a standardized stepped nutritional treatment process for patients with hematopoietic stem cell transportation, including nutritional risk screening and assessment, standardized nutritional treatment implementation, therapeutic effect follow-up and monitoring, family nutritional treatment follow-up, etc

Detailed Description

Standardized nutrition therapy for patients with hematopoietic stem cell transportation should follow the principle of sequential treatment of nutrition, which is the preferred scheme with individualized dietary advice or oral nutritional supplement, if their energy intake will not reach 60% of the goal level during the transplanting, then supplementary parenteral nutrition or total parenteral nutrition is needed. The standardized nutrition therapy aims to improve quality of life and long-term survival rate of patients, reduce the complications and social burden of disease.

Study Timeline

• Status Verified: 2020-09
• Study First Submitted: 2020-10-09
• Study First Submitted QC: 2020-10-09
• Last Update Submitted: 2020-10-09
• Study First Posted: 2020-10-19
• Last Update Posted: 2020-10-19
• Study Start: 2021-01-01
• Primary Completion: 2021-12-31
• Study Completion: 2022-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• • Patients treated with HSCT

Exclusion Criteria

• nothing

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
test group	dietary advice, oral nutritional supplement, supplementary parenteral nutrition or total parenteral nutrition	all the patients treated with HSCT are with nutrition risk, so they will be all included to accept nutrition therapy.

Primary Outcome Measures

Name	Time	Method
Improvement of nutritional status	4 months	We collect the body composition and grip strength of every HSCTpatients. Body composition include the muscle and fat contents.They are all measured as kilogram. (kg). Specific nutritional guidelines will be provided based on body composition results
Improvement of quality of life	4 months	We asked each patient to complete the quality of life scale for every HSCTpatient. There are 32 questions in the scale, and each question has 4-7 options. The higher the score, the heavier it is.We will decide whether to give psychological intervention based on the score.

Trial Locations

Locations (1)

Feng; 🇨🇳 Changsha, Hunan, China