Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Association Between Sleep and POD
研究概览
简要总结
The investigators are performing this research study to understand the role of sleep disturbance on the incidence/severity of delirium after surgery. The investigators will study the brain using a polysomnography device (PSG), which records the brain's electrical activity during sleep.
详细描述
During this study, PSG recordings will be collected and a sleep questionnaire will be administered to participants on the night before surgery in order to establish level of preexisting sleep disturbance. Delirium assessments will be conducted during the postoperative period. On postoperative days 0 and 1, blood will be collected for analysis. Further cognitive, quality of life and pain questionnaires will be administered perioperatively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Over 60 years of age
- •Inpatient and scheduled for surgical procedure at MGH
排除标准
- •Blindness, deafness or the inability to speak English
- •Inability to provide informed consent
- •Objective Drop Criteria
- •Post-operative intubation greater than 24 hours
结局指标
主要结局
Association Between Sleep and POD
时间窗: Night before surgery, approximately 13 hours
Duration of sleep in delirious vs non-delirious patients
次要结局
- Burst Suppression Ratio(Length of surgery (2-12 hours))
研究者
Oluwaseun Johnson-Akeju, MD, MMSc
Associate Professor of Anaesthesia
Massachusetts General Hospital