KCT0003462招募中未知
Development of a new dosing strategy of vancomycin using target concentration-controlled infusion
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 386
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 20(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •1st group, Development of a pharmacokinetic model for vancomycin in ICU patients with normal renal function or mild decreased renal function.
- •1. Patients over 20 years of age.
- •2. Patients who hospitalized in surgical intensive care unit of the Asan medical center.
- •3. Patients in clinical need for vancomycin administration
- •4. Patients over 60ml/min of glomerular filtration rate, on preoperative laboratory check.
- •5. Patients over 40 kg of body weight.
- •6. Patients who voluntarily agreed to be enrolled to the clinical research, or the case which the protector of the patient agreed to be enrolled to the clinical research, instead of the sedated patient.
- •- 2nd group, Development of a pharmacokinetic model for vancomycin in ICU patients with CRRT
- •1. Patients over 20 years of age.
- •2. Patients who hospitalized in surgical intensive care unit of the Asan medical center.
- •3. Patients in clinical need for vancomycin administration
- •4. Patients who receiving continuous renal replacement therapy(CRRT).
- •5. Patients over 40 kg of body weight.
- •6. Patients who voluntarily agreed to be enrolled to the clinical research, or the case which the protector of the patient agreed to be enrolled to the clinical research, instead of the sedated patient.
- •- 3rd and 4th group, Comparison of vancomycin therapeutic effectiveness between standard administration method versus TCI method, in patients with normal renal function
- •1. Patients over 20 years of age.
- •2. Patients who hospitalized in surgical intensive care unit of the Asan medical center.
- •3. Patients in clinical need for vancomycin administration
- •4. Patients over 60ml/min of glomerular filtration rate, on preoperative laboratory check.
- •5. Patients over 40 kg of body weight.
- •6. Patients who voluntarily agreed to be enrolled to the clinical research, or the case which the protector of the patient agreed to be enrolled to the clinical research, instead of the sedated patient.
排除标准
- •- 1st group, Development of a pharmacokinetic model for vancomycin in ICU patients with normal renal function or mild decreased renal function.
- •1. Pregnant female, or female who breast-feeds her baby.
- •2. Patients who has history of hypersensitivity to the vancomycin.
- •3. Patients who has history of prior vancomycin administration, within 7 days of the clinical research enroll agreement.
- •4. Patients below 8 g/dl of hemoglobin concentration.
- •5. Patients below 60ml/min of glomerular filtration rate, on preoperative laboratory check.
- •6. Other in-appropriative patients under the researcher's decision.
- •- 2nd group, Development of a pharmacokinetic model for vancomycin in ICU patients with CRRT
- •1. Pregnant female, or female who breast-feeds her baby.
- •2. Patients who has history of hypersensitivity to the vancomycin.
- •3. Patients who has history of prior vancomycin administration, within 7 days of the clinical research enroll agreement.
- •4. Patients below 8 g/dl of hemoglobin concentration.
- •5. Other in-appropriative patients under the researcher's decision.
- •- 3rd and 4th group, Comparison of vancomycin therapeutic effectiveness between standard administration method versus TCI method, in patients with normal renal function
- •1. Pregnant female, or female who breast-feeds her baby.
- •2. Patients who has history of hypersensitivity to the vancomycin.
- •3. Patients who has history of prior vancomycin administration, within 7 days of the clinical research enroll agreement.
- •4. Patients below 8 g/dl of hemoglobin concentration.
- •5. Patients below 60ml/min of glomerular filtration rate, on preoperative laboratory check.
- •6. Other in-appropriative patients under the researcher's decision.
研究者
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