Rebound Pain Following Surgery With Regional Anesthesia Block

Completed

• Conditions: Regional Anesthesia Morbidity; Pain, Postoperative
• Interventions: Other: Numerical Pain Scales

• Registration Number: NCT05357105
• Lead Sponsor: University of Alberta

Brief Summary

For some kinds of surgery, Anesthesiologists provide nerve blocks (regional anesthesia) to reduce pain from surgery by injecting freezing medication around deep nerves with ultrasound. Nerve blocks help with pain control following surgery and reduce the amount of strong opioids needed but relatively little research has focused on the pain that occurs once the nerve block has worn off. This is called rebound or transition pain.

This research study will prospectively collect data including pain scores before, during and after nerve blocks are given for surgery. We will look at the type of nerve blocks and other analgesia medications used with the aim of quantifying rebound pain to better understand how to limit it's impact on quality postoperative pain control.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-01-14
• Study First Submitted QC: 2022-04-26
• Study First Posted: 2022-05-02
• Study Start: 2023-01-10
• Primary Completion: 2025-01-15
• Study Completion: 2025-01-15
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-03
• Last Update Posted: 2025-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 119

Inclusion Criteria

• Age 18-75 years
• Receiving peripheral nerve block as part for anesthesia/analgesia as part of standard perioperative care for surgery performed at University of Alberta Hospital during a 6 month period
• Elective and emergency surgery

Exclusion Criteria

• Inability to consent to participate in the study (illiteracy, <7th grade education)
• Contraindication/history of hypersensitivity to local anesthetics

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Regional Nerve Block Patients	Numerical Pain Scales	Patients who receive regional nerve blocks as part of the anesthetic management prior to surgery.

Primary Outcome Measures

Name	Time	Method
Numerical Pain Scale	2-3 times per patient over the course of a nerve block, up to 48 hours after the stop of the block (single shot or cessation of nerve catheter)

Trial Locations

Locations (1)

University of Alberta Hospital; 🇨🇦 Edmonton, Alberta, Canada