Investigation of Potential Retinal Toxicity Associated With Hair Dye Products Containing pPD Type Aromatic Amines
Not Applicable
Completed
- Conditions
- MEK Inhibitor-Associated Serous Retinopathy
- Interventions
- Device: OCT-B scan
- Registration Number
- NCT04222387
- Lead Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
- Brief Summary
Hair dye products could induce minimal forms of MEKAR retinopathies (Mitogen-activated Extracellular signal-regulated Kinase - inhibitors associated retinopathies). These minimal forms of MEKAR are likely to be underdiagnosed, since the associated visual loss is usually mild and so this condition should be considered when patients report blurred vision. The aim of the study is to analyze whether in the current population that dyes the hair, minimal forms that go unnoticed by MEKAR retinopathies can be induced.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
- Hair dye up to one month before the inclusion
- Hair dye product containing aromatic amines
Exclusion Criteria
- Pregnant or lactating woman
- Retinal pathology already known, or central serous choroiditis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Participants with hair dye OCT-B scan Hair dye product with pPD Type Aromatic Amines used up to 1 month before
- Primary Outcome Measures
Name Time Method % of patients with MEKAR retinopathy detected on OCT-B scan Day of inclusion, up to one month month after the last hair dye Physiological parameter : Serous retinal detachment at the posterior pole, detected on OCT-B scan
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Fondation A de Rothschild
🇫🇷Paris, France