Emergence time following target-controlled versus manual controlled propofol infusion in patients undergoing endoscopic trans-sphenoidal pituitary surgery: A Prospective, Randomized, Controlled study

Smooth and early emergence from anaesthesia prevents sudden rise in blood pressure and risk of complications such as bleeding while early recovery facilitates prompt neurological assessment and treatment of complications.  This study aims to compare the emergence time (from anaesthesia) between the target-controlled infusion (TCI) versus manual-controlled infusion (MCI) techniques of propofol infusion in patients undergoing elective endoscopic trans-sphenoidal pituitary surgery. The study will also asses the intraoperative hemodynamic variability, propofol and fentanyl consumption, time to tracheal extubation and aldretes’s score at 5 min between the two groups. The present study will provide insight whether use of target controlled infusion technique for propofol infusion will result in early and smooth recovery from anaesthesia over manual controlled technique  in patients undergoing elective endoscopic trans-sphenoidal pituitary surgery.