The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Procedure: mechanical ventilation

• Registration Number: NCT00141440
• Lead Sponsor: Policlinico Hospital

Brief Summary

The investigators' aim is to study the effect of cycling off criteria during pressure support ventilation in COPD patients at two levels of PEEP and PSV.

Detailed Description

In this study two levels of cycling off criteria at two levels of PEEP and PSV were tested in term of gas exchange, respiratory mechanics, work of breathing and patient comfort.

Study Timeline

• Study Start: 2005-07
• Study First Submitted: 2005-08-31
• Study First Submitted QC: 2005-08-31
• Study First Posted: 2005-09-01
• Primary Completion: 2007-03
• Study Completion: 2007-03
• Status Verified: 2008-09
• Last Update Submitted: 2009-12-29
• Last Update Posted: 2009-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

• Stable COPD patients during invasive mechanical ventilation

Exclusion Criteria

• Hemodynamic instability,
• Paralysis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	mechanical ventilation	COPD patients

Primary Outcome Measures

Name	Time	Method
Respiratory mechanics, gas exchange	2 minutes

Secondary Outcome Measures

Name	Time	Method
Comfort of breathing	2 minutes

Trial Locations

Locations (1)

Ospedale Sacco; 🇮🇹 Milano, Italy