The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Not Applicable
Completed
- Conditions
- Chronic Obstructive Pulmonary Disease
- Registration Number
- NCT00141440
- Lead Sponsor
- Policlinico Hospital
- Brief Summary
The investigators' aim is to study the effect of cycling off criteria during pressure support ventilation in COPD patients at two levels of PEEP and PSV.
- Detailed Description
In this study two levels of cycling off criteria at two levels of PEEP and PSV were tested in term of gas exchange, respiratory mechanics, work of breathing and patient comfort.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
- Stable COPD patients during invasive mechanical ventilation
Exclusion Criteria
- Hemodynamic instability,
- Paralysis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Respiratory mechanics, gas exchange 2 minutes
- Secondary Outcome Measures
Name Time Method Comfort of breathing 2 minutes
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie COPD exacerbation during pressure support ventilation?
How does varying PEEP and PSV levels affect respiratory mechanics in COPD patients on mechanical ventilation?
Are there specific biomarkers that predict patient comfort outcomes in NCT00141440 trial settings?
What adverse events are associated with cycling off criteria in COPD mechanical ventilation trials?
How does pressure support ventilation in NCT00141440 compare to standard weaning protocols for COPD patients?
Trial Locations
- Locations (1)
Ospedale Sacco
🇮🇹Milano, Italy
Ospedale Sacco🇮🇹Milano, Italy